GrantPostedDiscretionary

Mechanistic Research on Neuromodulation for Substance Use Disorders Treatment (R61/R33 Basic Experimental Studies with Humans Required)

National Institutes of Health
RFA-DA-24-034
Application Deadline
Aug 14, 2026
153 days left
Days Remaining
153
Until deadline
Award Ceiling
$500,000
Total Program Funding

Grant Opportunity Analysis

The National Institutes of Health (NIH), through the National Institute on Drug Abuse (NIDA), has announced a funding opportunity titled "Mechanistic Research on Neuromodulation for Substance Use Disorders Treatment" (R61/R33 Basic Experimental Studies with Humans Required). This initiative aims to encourage exploratory and developmental research focused on identifying and validating novel targets for non-invasive brain stimulation (NIBS) and understanding the neurobiological and cognitive responses that precede clinical outcomes such as reduced cravings or substance use. The funding is critical for advancing innovative methodologies in substance use disorder (SUD) research, with a maximum award of $600,000 available for the R61 phase over two years, and applications are due by August 14, 2026. For further inquiries, interested applicants can contact NIH Grants Information at grantsinfo@nih.gov or visit the opportunity's webpage at https://grants.nih.gov/grants/guide/rfa-files/RFA-DA-24-034.html.

Eligible Applicants

Others
Additional Eligibility Information

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Grant Documents

1 Files
RFA-DA-24-034.html
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AI Summary
The National Institutes of Health (NIH), through the National Institute on Drug Abuse (NIDA), has announced a funding opportunity aimed at advancing mechanistic research on non-invasive brain stimulation (NIBS) for treating substance use disorders (SUD). This notice encourages exploratory and developmental applications under the R61/R33 phased award mechanism. Proposals should focus on identifying and validating novel NIBS targets, understanding related neurobiological and cognitive responses that precede clinical outcomes such as cravings or substance use reduction. A critical requirement is the submission of a Plan for Enhancing Diverse Perspectives (PEDP) to ensure inclusivity during the research process. The maximum funding for the R61 phase is $600,000 over two years, with successful projects able to transition to the R33 phase for further funding. Applications are due by August 14, 2026. The initiative underscores the urgent need for innovative research methodologies to better understand the mechanisms underlying SUDs and support the development of effective treatment options, enhancing overall outcomes in public health.

Related Grant Opportunities

Project Timeline

postedOriginal Opportunity PostedSep 29, 2023
deadlineApplication DeadlineAug 14, 2026
expiryArchive DateSep 19, 2026

Funding Details

Award Ceiling
$500,000
No cost sharing required

Agency & Classification

Agency
National Institutes of Health(HHS-NIH11)
Funding Category
Health
Funding Instrument
Grant

Grantor Contact

CFDA Numbers

93.847

Official Sources