Cooperative AgreementPostedDiscretionary

Device Based Treatments for Substance Use Disorders (UG3/UH3 Clinical Trial Optional)

National Institutes of Health
PAR-23-253
Application Deadline
Aug 13, 2026
152 days left
Days Remaining
152
Until deadline
Award Ceiling
Total Program Funding

Grant Opportunity Analysis

The National Institutes of Health (NIH) is offering a funding opportunity aimed at advancing device-based treatments for Substance Use Disorders (SUDs) through a cooperative agreement. The initiative seeks to expedite the development and FDA approval of innovative neuromodulatory devices, with a focus on both pre-clinical and clinical phases, and encourages the exploration of existing devices approved for other conditions. This funding opportunity follows a two-phase approach (UG3/UH3), where the UG3 phase supports projects for up to two years, and the UH3 phase provides additional funding for successful projects for up to three more years. Applications open on November 18, 2023, with the first funding start date set for December 18, 2023. Eligible applicants include a wide range of institutions, and inquiries can be directed to NIH Grants Information at grantsinfo@nih.gov. For more details, visit the official announcement at https://grants.nih.gov/grants/guide/pa-files/PAR-23-253.html.

Eligible Applicants

Others
Additional Eligibility Information

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Grant Documents

2 Files
PAR-23-253-Full-Announcement.html
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PAR-23-253.html
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AI Summary
The Department of Health and Human Services, through the National Institutes of Health (NIH), announces a funding opportunity aimed at advancing device-based treatments for Substance Use Disorders (SUDs). The goal is to expedite the development and FDA approval of innovative neuromodulatory devices that can effectively treat SUDs. This funding covers both pre-clinical and clinical phases and encourages investigating existing devices already approved for other conditions. The funding opportunity involves a two-phase approach (UG3/UH3), where the UG3 phase supports projects for up to two years with specific milestones, and the UH3 phase provides further funding for successful projects for an additional three years. Important dates include an application opening on November 18, 2023, and the first funding start date on December 18, 2023. Applicants must ensure compliance with NIH guidelines and can submit their applications through Grants.gov. Eligible institutions range from higher education to nonprofit organizations and foreign entities. The announcement emphasizes the need for thorough understanding of device interactions with brain circuits, potential side effects, and longevity of treatment effects. Ultimately, the initiative seeks to fill existing gaps in SUD therapies and improve public health outcomes significantly.

Related Grant Opportunities

Project Timeline

postedOriginal Opportunity PostedAug 18, 2023
deadlineApplication DeadlineAug 13, 2026
expiryArchive DateSep 18, 2026

Funding Details

No cost sharing required

Agency & Classification

Agency
National Institutes of Health(HHS-NIH11)
Funding Category
Health
Funding Instrument
Cooperative Agreement

Grantor Contact

CFDA Numbers

93.279

Official Sources