The National Institutes of Health (NIH) has announced a Notice of Funding Opportunity (NOFO) for the Human Virome Program, which aims to develop innovative tools and methods for characterizing the human virome and understanding its impact on health and disease. This initiative seeks to address technological challenges in identifying and analyzing human-associated viruses, inviting applicants to propose projects that enhance the study of the human virome through novel tools and bioinformatics methods. The program is significant for advancing knowledge that could lead to new health-related biomarkers and therapeutic strategies, with NIH planning to commit approximately $2.5 million to fund 4-5 awards, each with a maximum budget of $350,000 per year for up to four years. Applications are due by January 27, 2025, with the earliest project start date anticipated for July 2025; for further inquiries, interested parties can contact NIH Grants Information at grantsinfo@nih.gov.