The National Institutes of Health (NIH) is offering a grant opportunity titled "Early Stage Investigator HIV/AIDS Research Using Nonhuman Primate (NHP) Models (R21 Clinical Trial Not Allowed)" aimed at supporting preclinical HIV/AIDS research conducted by Early Stage Investigators (ESIs). This initiative seeks to empower ESIs, who are within 10 years of their terminal degree or residency completion and possess at least two years of postdoctoral experience, to explore innovative research directions using NHP models, thereby enhancing their competitiveness for larger NIH grants. The funding, capped at $400,000 over two years, is intended for projects that align with the NIH Strategic Plan for HIV and HIV-Related Research, focusing on critical areas such as reducing HIV incidence and developing new therapies. Interested applicants must adhere to NIH guidelines and submit their proposals by September 7, 2025, with further inquiries directed to grantsinfo@nih.gov.