New Therapeutic Strategies for Genital Herpes (R21/R33 Clinical Trial Not Allowed)
ID: 356714Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Eligible Applicants

Others

Funding Category

Health

Funding Instrument

Grant

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes

Original Source

https://grants.gov/search-results-detail/356714

Additional Information

http://grants.nih.gov/grants/guide/rfa-files/RFA-AI-24-068.html
Timeline
    Description

    The National Institutes of Health (NIH) is offering a funding opportunity titled "New Therapeutic Strategies for Genital Herpes" under the R21/R33 Clinical Trial Not Allowed mechanism. This initiative aims to stimulate research into innovative treatments that suppress virus shedding, minimize lesion formation, and reduce transmission risks associated with genital herpes, focusing on the development of new antivirals, therapeutic vaccines, and gene editing technologies. With a total budget of $3.5 million planned to support 7-10 grants, eligible applicants include a wide range of organizations such as academic institutions, nonprofits, and local governments. Interested parties must submit their applications by January 31, 2025, and can find additional information and application guidelines at the NIH grants website or contact NIH Grants Information at grantsinfo@nih.gov.

    Point(s) of Contact
    grantsinfo@nih.gov
    Files
    Title
    Posted
    RFA-AI-24-068.html
    The Department of Health and Human Services, through the National Institute of Allergy and Infectious Diseases (NIAID), invites proposals for the R21/R33 Phased Innovation Award aimed at developing new therapeutic strategies for genital herpes. The funding opportunity seeks to stimulate research into effective treatments to suppress virus shedding, minimize lesion formation, and reduce transmission risks. Eligible applicants include academic institutions, nonprofits, and local governments, with a total budget of $3.5 million planned to support 7-10 grants. The R21 phase allows for up to $275,000 in direct costs over two years, followed by a potential three-year R33 phase with an expected budget not exceeding $300,000 annually. Applications must adhere to a milestone-driven approach, progressing to the R33 phase contingent upon meeting specific R21 milestones. The submission process requires compliance with NIH application instructions and a focus on innovative therapeutic candidates including improved antivirals, therapeutic vaccines, and gene editing technologies. The overarching goal is to advance knowledge in HSV treatment, as current options are limited and do not effectively control recurrent infections or transmission risks. The initiative is aligned with the NIH’s strategic priorities to enhance herpes simplex virus research and treatment options.
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