The National Institutes of Health (NIH), through the National Institute of Allergy and Infectious Diseases (NIAID), is offering a funding opportunity titled "Understanding Mechanisms and Outcomes of Trained Immunity (R01 Clinical Trial Not Allowed)." This grant aims to support research that enhances the understanding of trained immunity, focusing on its mechanisms, biomarkers, and implications for immune system development, vaccine responses, and conditions such as autoimmunity and allergic diseases. The initiative is significant for advancing immunological research and public health, encouraging applications from a diverse range of eligible organizations, including higher education institutions and nonprofits. Interested applicants should note that the application deadline is June 5, 2024, with the funding opportunity closing on January 8, 2027. For further inquiries, applicants can contact NIH Grants Information at grantsinfo@nih.gov or visit the additional information link at https://grants.nih.gov/grants/guide/pa-files/PAR-24-112.html.