Elucidating Immunometabolic Responses to HIV Infection that Increase TB or HBV Risk (R01 Clinical Trial Not Allowed)
ID: 357821Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Eligible Applicants

Others

Funding Category

Health

Funding Instrument

Grant

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes

Original Source

https://grants.gov/search-results-detail/357821

Additional Information

http://grants.nih.gov/grants/guide/pa-files/PAR-25-315.html
Timeline
    Description

    The National Institutes of Health (NIH) is offering a funding opportunity titled "Elucidating Immunometabolic Responses to HIV Infection that Increase TB or HBV Risk (R01 Clinical Trial Not Allowed)" aimed at supporting research into the immunometabolic changes induced by HIV that may elevate the risk of tuberculosis (TB) and hepatitis B virus (HBV) in individuals on combination antiretroviral therapy (cART). This initiative seeks to fund investigator-led studies that explore the long-term effects of HIV-related alterations in immune metabolism on disease progression and treatment responses, with a focus on identifying biomarkers and innovative therapies to mitigate these risks. The grant is open to a wide range of eligible applicants, including higher education institutions, non-profits, and for-profit organizations, with no cost-sharing requirements. Interested parties should note that the application submission deadlines range from April 2025 to January 2028, and they can direct inquiries to NIH Grants Information at grantsinfo@nih.gov. For further details, applicants can refer to the full announcement available at https://grants.nih.gov/grants/guide/pa-files/PAR-25-315.html.

    Point(s) of Contact
    grantsinfo@nih.gov
    Files
    Title
    Posted
    PAR-25-315-Full-Announcement.html
    PAR-25-315.html
    The Department of Health and Human Services, through the National Institutes of Health (NIH), is issuing a funding opportunity (PAR-25-315) for research aimed at understanding immunometabolic responses to HIV infection that elevate the risk of tuberculosis (TB) and hepatitis B virus (HBV) in individuals undergoing combination antiretroviral therapy. This initiative will support investigator-led studies focused on the long-term impacts of HIV-induced changes in immune metabolism on disease progression and treatment responses. Eligible applicants include higher education institutions, non-profits, and for-profit organizations, with awards being made based on NIH appropriations and the merit of applications. Clinical trials are not permitted under this grant. The funding goal encompasses both basic and clinical research to improve strategies against infectious diseases and aid public health efforts. Current deadlines for submissions range from April 2025 to January 2028, emphasizing careful matching of application timing and compliance with intricate submission guidelines. Successful projects will contribute to identifying biomarkers and innovative therapies to combat TB and HBV risks associated with HIV. This funding program highlights the NIH's commitment to advancing biomedical research in infectious diseases.
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