The National Institutes of Health (NIH), through the National Institute of Allergy and Infectious Diseases (NIAID), is inviting proposals for investigator-initiated Program Project (P01) applications focused on critical research areas related to infectious diseases and immune-mediated conditions. Applicants are required to submit proposals that include at least two related research projects sharing a common theme, along with an administrative core, while clinical trials are not permitted under this funding opportunity. This initiative aims to enhance collaborative research efforts to address significant health challenges, including the biology of infectious microbes and the development of vaccines and therapeutics. Interested applicants can find more information and submission guidelines at the provided link, with the next application deadlines set for January 11 and June 8, 2023, and a final close date of September 7, 2025. For inquiries, contact NIH Grants Information at grantsinfo@nih.gov.