The National Institutes of Health (NIH) has announced a funding opportunity titled "New Approaches for Measuring Brain Changes Across Longer Timespans" under the grant number PAR-25-272. This initiative aims to support multidisciplinary research that develops innovative methods for measuring brain activity and changes over extended periods, focusing on neurodevelopment across various age groups to understand how early brain changes can predict later health outcomes. The funding available is capped at $275,000 over two years, with direct costs limited to $200,000 in any single year, and applications must include data from at least two timepoints along with a Plan for Enhancing Diverse Perspectives. The application submission opens on January 16, 2025, with a closing date of May 7, 2027, and interested applicants can reach out to NIH Grants Information at grantsinfo@nih.gov for further inquiries.

PAR-25-272-Full-Announcement.html

PAR-25-272.html

The Department of Health and Human Services, in collaboration with various National Institutes of Health components, has issued a Notice of Funding Opportunity (NOFO) titled "New Approaches for Measuring Brain Changes Across Longer Timespans" under funding opportunity number PAR-25-272. The initiative aims to foster innovative, multidisciplinary research that develops novel methods to study brain activity and changes over extended periods. The research should focus on measuring neurodevelopment across different age groups, helping to understand how early brain changes can predict health outcomes in later life. Applications can utilize human participants or animal models and must include data from at least two timepoints. Additionally, proposals need to outline a Plan for Enhancing Diverse Perspectives to improve inclusivity in research. The funding available is capped at $275,000 over two years, with direct costs limited to $200,000 in any single year. The application submission opens on January 16, 2025, with deadlines extending to summer 2027. This funding opportunity reflects the NIH's commitment to advancing knowledge in aging and brain health through innovative research methodologies and diverse team collaborations.

https://grants.nih.gov/grants/guide/pa-files/PAR-25-272.html

The purpose of this funding opportunity is to encourage multidisciplinary investigators to submit applications developing exploratory, highly novel new approaches, or innovative applications of existing approaches to measure brain activity, connectivity, genomics, or other aspects across the age spectrum of neurodevelopment. The overarching goal is to extend our understanding of brain development and aging, including studies of the neurodevelopmental origins of later health and disease, by improving repeated measures across longer epochs of the lifespan to better predict outcomes at later ages. . Research can include healthy human participants of any age, specific clinical groups such those with cognitive, motor, or affective regulation challenges, and/or animal research on these domains of function. The studies can focus on longitudinal neuroanatomical or functional changes at any level, including genetics/genomics, single cells, connectomics, neural population activity patterns, and others. This funding opportunity is intended to encourage technological and conceptual innovation through this high risk, high reward funding mechanism to develop highly innovative ideas that either lack preliminary data or need additional preliminary data

See Section VII. Agency Contacts within the full opportunity announcement for all other inquires.

NIH Grants Information&lt;br/&gt;grantsinfo@nih.gov

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