NINDS Exploratory Clinical Trials (UG3/UH3 Clinical Trial Required)
ID: 339577Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Eligible Applicants

Others

Funding Category

Health

Funding Instrument

Cooperative Agreement

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes

Original Source

https://grants.gov/search-results-detail/339577

Additional Information

http://grants.nih.gov/grants/guide/pa-files/PAR-22-142.html
Timeline
    Description

    The National Institutes of Health (NIH), through the National Institute of Neurological Disorders and Stroke (NINDS), has announced a funding opportunity for investigator-initiated exploratory clinical trials (UG3/UH3) aimed at addressing neurological disorders. This initiative seeks applications for Phase 1 and Phase 2 trials that may involve drugs, biologics, surgical, behavioral, or rehabilitation therapies, with a focus on generating data to support future efficacy trials. The funding is open to a diverse range of eligible applicants, including universities, nonprofits, and tribal organizations, emphasizing the importance of rigorous methodologies and scientific rationale in the proposals. Interested applicants should note that the application deadline is March 10, 2025, and can find further details and contact information at the provided NIH link: http://grants.nih.gov/grants/guide/pa-files/PAR-22-142.html.

    Point(s) of Contact
    OERWebmaster03@od.nih.gov
    Files
    Title
    Posted
    PAR-22-142.html
    The Department of Health and Human Services, through the National Institutes of Health (NIH) and specifically the National Institute of Neurological Disorders and Stroke (NINDS), has issued a Funding Opportunity Announcement (FOA) for investigator-initiated exploratory Phase 1 and Phase 2 clinical trials (UG3/UH3). This reissue of announcement PAR-21-236 aims to support trials addressing neurological disorders through various interventions including drugs, biologics, surgical, behavioral, and rehabilitation therapies. The funding seeks applications with strong scientific rationale and rigorous methodologies that ensure safety, efficacy, and transparency. Key details include the eligibility of diverse organizations (e.g., universities, nonprofits, government entities) and the importance of early phase trials for planning future Phase 2 trials. The review process emphasizes the proposal's significance, innovative approach, and demonstrated capacity of the research team. Applications must adhere to specific NIH-guided standards for reporting and recruitment diversity. Overall, the FOA underscores the NIH's commitment to advancing neuroscience research through well-designed clinical trials that will generate data crucial for developing new therapeutic interventions for neurological disorders.
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