NIH SIREN Neurologic Clinical Trials (UG3/UH3 - Clinical Trial Required)
ID: 345880Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Eligible Applicants

Others

Funding Category

Health

Funding Instrument

Cooperative Agreement

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes

Original Source

https://grants.gov/search-results-detail/345880

Additional Information

http://grants.nih.gov/grants/guide/pa-files/PAR-23-090.html
Timeline
    Description

    The National Institutes of Health (NIH) is offering a funding opportunity titled "NIH SIREN Neurologic Clinical Trials (UG3/UH3 - Clinical Trial Required)" aimed at supporting multi-center clinical trials focused on neurological emergencies, such as traumatic brain injuries and seizures. This initiative encourages applications for clinical trials that will be conducted within the NIH SIREN Network, with successful applicants collaborating closely with the NIH SIREN Clinical Coordinating Center (CCC) and Data Coordinating Center (DCC) to implement their proposed trials efficiently. The funding, administered through a cooperative agreement mechanism, emphasizes pragmatic trial designs that address urgent public health needs in neurological care settings. Interested applicants, including a wide range of eligible institutions, must submit letters of intent 30 days prior to application deadlines, with the final submission date set for March 6, 2026. For further inquiries, applicants can contact NIH Grants Information at grantsinfo@nih.gov.

    Point(s) of Contact
    grantsinfo@nih.gov
    Files
    Title
    Posted
    PAR-23-090-Full-Announcement.html
    PAR-23-090.html
    The Department of Health and Human Services announces a funding opportunity, PAR-23-090, aimed at supporting multi-center clinical trials within the NIH SIREN Network, focused on neurological emergencies such as traumatic brain injuries and seizures. The funding will be administered through a UG3/UH3 cooperative agreement mechanism, requiring clinical trials to test the efficacy of interventions. The SIREN Network will provide essential infrastructure, managing clinical operations and data through its Clinical Coordinating Center (CCC) and Data Coordinating Center (DCC). Applications are encouraged from institutions not currently part of the SIREN network. Key dates for submission include letters of intent due 30 days prior to application dates from June 2023 through February 2026. Eligible institutions range from higher education entities to nonprofits and for-profit organizations. Applicants must ensure compliance with specific instructions surrounding data management, clinical trials, and responsible usage of the SIREN framework. There will be a focus on pragmatic trial designs that efficiently meet scientific needs while addressing public health concerns. Overall, this initiative underscores a collaborative approach to advancing research in urgent neurological care settings.
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