Prospective Observational Comparative Effectiveness Research in Clinical Neurosciences (UG3/UH3 Clinical Trial Not Allowed)
ID: 358084Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Eligible Applicants

Others

Funding Category

Health

Funding Instrument

Cooperative Agreement

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes

Original Source

https://grants.gov/search-results-detail/358084

Additional Information

http://grants.nih.gov/grants/guide/pa-files/PAR-25-048.html
Timeline
    Description

    The National Institutes of Health (NIH) is offering a funding opportunity for prospective observational comparative effectiveness research (CER) in clinical neurosciences under the funding opportunity number PAR-25-048. This initiative aims to support investigator-initiated studies that evaluate the effectiveness of existing interventions, treatments, or diagnostic approaches for neurological disorders in real-world settings. The funding mechanism is a cooperative agreement divided into two phases: a 2-year UG3 planning phase and a 5-year UH3 implementation phase, contingent on meeting scientific milestones. Applications are encouraged from a diverse range of institutions, particularly those focusing on underrepresented populations and diseases. Key deadlines include an application due date of February 19, 2025, and a funding expiration on September 8, 2025. For further inquiries, interested parties can contact NIH Grants Information at grantsinfo@nih.gov.

    Point(s) of Contact
    grantsinfo@nih.gov
    Files
    Title
    Posted
    PAR-25-048-Full-Announcement.html
    PAR-25-048.html
    The Department of Health and Human Services is offering funding opportunities through the National Institutes of Health (NIH) for prospective observational comparative effectiveness research (CER) in clinical neurosciences under funding opportunity number PAR-25-048. This initiative aims to support investigator-initiated studies that compare the effectiveness of existing interventions, treatments, or diagnostic approaches specifically in real-world settings for neurological disorders. The funding mechanism is a cooperative agreement, divided into two phases: a 2-year UG3 planning phase and a 5-year UH3 implementation phase contingent on meeting scientific milestones. Applications are encouraged from diverse institutions, emphasizing those focusing on underrepresented populations and diseases. Key dates include an application due date of February 19, 2025, and a funding expiration on September 8, 2025, with specific instructions for application preparation and submission through Grants.gov. Substantial NIH involvement is expected during project execution to ensure scientific rigor and compliance with established policies. Overall, this funding opportunity seeks to generate valuable real-world data to enhance clinical decision-making and improve treatment strategies for neurological disorders while addressing significant healthcare disparities.
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