The National Institutes of Health (NIH) is offering the "NINDS Renewal Awards of SBIR Phase II Grants (Phase IIB) for Clinical Trials and Clinical Research," aimed at supporting U.S. small businesses in advancing medical technology and biotechnology projects toward commercialization, particularly in the neurological field. This funding opportunity encourages applications from small business concerns that have previously received NIH SBIR or STTR Phase II awards, focusing on projects that evaluate drugs, biologics, devices, or diagnostics, as well as surgical, behavioral, or rehabilitation therapies. The initiative seeks to bridge the funding gap for clinical trials, promoting partnerships with third-party investors and requiring a detailed Commercialization Plan from applicants. The total funding support for a Phase II award is capped at $2,045,816, with applications due by April 5, 2027. Interested parties can find more information and submit applications through Grants.gov or the NIH ASSIST system, and inquiries can be directed to grantsinfo@nih.gov.