The National Institutes of Health (NIH) is offering a funding opportunity under the HEAL Initiative aimed at enhancing the implementation of substance use preventive services. This initiative seeks applications for research that addresses the gap between research and practice in substance misuse prevention, focusing on developing sustainable and effective service delivery strategies. Given the ongoing opioid crisis, the importance of this research is underscored by the need for innovative approaches to integrate evidence-based prevention within existing systems and to enhance workforce capacity. Successful applications may receive funding of up to $4.65 million over a maximum project period of five years, with direct costs not exceeding $800,000 per year. Interested applicants can find more information and submit inquiries via grantsinfo@nih.gov, with the application deadline set for January 16, 2026.