The National Institutes of Health (NIH), through the National Institute on Drug Abuse (NIDA), has announced the Avenir Award Program for Genetics or Epigenetics of Substance Use Disorders (DP1 Clinical Trial Optional), aimed at supporting early-stage investigators proposing innovative research in addiction genetics or epigenetics. This funding opportunity encourages the development of new methodologies and ideas that can advance the understanding and treatment of substance use disorders, with a focus on addressing significant scientific challenges in the field. Eligible applicants include a diverse range of organizations, such as higher education institutions and nonprofits, with budgets capped at $300,000 annually for up to five years. Applications are due by September 25, 2023, and interested parties can find more information by contacting NIH Grants Information at grantsinfo@nih.gov or visiting the program's webpage at https://grants.nih.gov/grants/guide/pa-files/PAR-23-021.html.