Clinical Trial Readiness for Rare Diseases, Disorders, and Syndromes (R21 Clinical Trial Not Allowed)
ID: 347499Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Award Range

$0 - $275K

Eligible Applicants

Others

Funding Category

Income Security and Social Services

Funding Instrument

Grant

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes

Original Source

https://grants.gov/search-results-detail/347499

Additional Information

http://grants.nih.gov/grants/guide/pa-files/PAR-23-159.html
Timeline
    Description

    The National Institutes of Health (NIH) is offering a funding opportunity titled "Clinical Trial Readiness for Rare Diseases, Disorders, and Syndromes" under the R21 Exploratory/Developmental Research Grant initiative. This grant aims to support projects that address critical barriers to clinical trial readiness for rare diseases, which are defined as conditions affecting fewer than 200,000 individuals in the U.S., by developing and validating biomarkers, clinical outcome measures, and understanding disease natural history. The initiative is crucial for enhancing the progression of therapeutics toward clinical trials, addressing significant public health concerns related to the limited treatment options available for rare diseases. Eligible applicants can receive up to $275,000 for a two-year project, with applications due by October 17, 2024. For further inquiries, interested parties can contact NIH Grants Information at grantsinfo@nih.gov or visit the opportunity's webpage at https://grants.nih.gov/grants/guide/pa-files/PAR-23-159.html.

    Point(s) of Contact
    grantsinfo@nih.gov
    Files
    Title
    Posted
    PAR-23-159-Full-Announcement.html
    PAR-23-159.html
    The Department of Health and Human Services announces a funding opportunity through the NIH to enhance clinical trial readiness for rare diseases through the R21 Exploratory/Developmental Research Grant initiative. This request for proposals invites researchers to submit applications aimed at addressing barriers to effective clinical trials for rare diseases, defined as those affecting fewer than 200,000 individuals in the U.S. Key areas of focus include developing and validating biomarkers and clinical outcome assessment measures, understanding disease natural history, and fostering partnerships among stakeholders such as academic entities, industry, and patient groups. Applications are expected to leverage existing research resources and must not propose clinical trials themselves. Eligible organizations include higher education institutions, nonprofits, and government entities. Budgets can reach up to $275,000 for a two-year project, with the goal of facilitating the progression of therapeutics toward clinical trials. The initiative operates under rigorous guidelines to ensure compliance with NIH policies. The urgency for clinical trial readiness is underscored, addressing critical public health concerns associated with rare diseases—acknowledging the significant unmet medical needs and the limited treatments available.
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