GrantPostedDiscretionary

Pilot Projects Investigating Understudied Proteins Associated with Rare Diseases (R03 Clinical Trial Not Allowed)

National Institutes of Health
PAR-25-122
Application Deadline
Nov 16, 2027
612 days left
Days Remaining
612
Until deadline
Award Ceiling
$100,000
Total Program Funding

Grant Opportunity Analysis

The National Institutes of Health (NIH) is offering a funding opportunity titled "Pilot Projects Investigating Understudied Proteins Associated with Rare Diseases," aimed at supporting pilot projects that explore the roles of understudied proteins linked to rare diseases. The objective is to generate preliminary data and tools related to these proteins, which are associated with rare diseases affecting fewer than 200,000 individuals in the U.S., thereby facilitating innovative research that could lead to new drug targets and treatments. Eligible applicants include a wide range of institutions, including educational and nonprofit organizations, government entities, and small businesses, with funding available up to $100,000 for projects that can be completed within one year. Interested parties can find more information and apply by contacting NIH Grants Information at grantsinfo@nih.gov, with applications due by November 16, 2027.

Eligible Applicants

Others
Additional Eligibility Information

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Grant Documents

1 Files
PAR-25-122.html
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AI Summary
The Department of Health and Human Services, through the National Institutes of Health (NIH), is soliciting applications for pilot projects aimed at studying understudied proteins linked to rare diseases. This funding opportunity, titled "Pilot Projects Investigating Understudied Proteins Associated with Rare Diseases," is part of the R03 Small Grant Program and allows for projects that can be completed in one year with a budget of up to $100,000 in direct costs. The goal is to generate preliminary data on eligible understudied proteins, which are proteins with limited biological characterization that have known associations with rare diseases affecting fewer than 200,000 individuals in the U.S. Eligible applicants include various educational and nonprofit institutions, government entities, and small businesses. The funding mechanism aims to facilitate innovative research that identifies new drug targets and catalyzes further studies in translational science, directly contributing to the development of treatments for the estimated 10,000 rare diseases. Applications must provide evidence linking the proposed understudied protein to a rare disease and are encouraged to employ non-animal methodologies. The initiative reflects NIH's commitment to enhancing biomedical research that addresses critical gaps in understanding rare conditions related to the human proteome.

Related Grant Opportunities

Project Timeline

postedOriginal Opportunity PostedOct 28, 2024
deadlineApplication DeadlineNov 16, 2027
expiryArchive DateDec 22, 2027

Funding Details

Award Ceiling
$100,000
No cost sharing required

Agency & Classification

Agency
National Institutes of Health(HHS-NIH11)
Funding Category
Health
Funding Instrument
Grant

Grantor Contact

CFDA Numbers

93.855

Official Sources