Individually Measured Phenotypes to Advance Computational Translation in Mental Health (IMPACT-MH) (U01 Clinical Trial Optional)
ID: 355145Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Award Range

$0 - $3M

Eligible Applicants

Others

Funding Category

Health

Funding Instrument

Cooperative Agreement

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes

Original Source

https://grants.gov/search-results-detail/355145

Additional Information

http://grants.nih.gov/grants/guide/rfa-files/RFA-MH-25-195.html
Timeline
    Description

    The National Institutes of Health (NIH) has announced a funding opportunity titled "Individually Measured Phenotypes to Advance Computational Translation in Mental Health (IMPACT-MH)," aimed at promoting innovative research in mental health through the development of individualized clinical signatures. This initiative encourages applicants to propose novel behavioral tasks and utilize existing datasets to enhance clinical decision-making and patient outcomes in mental disorders, emphasizing the need for diverse research teams and a Plan for Enhancing Diverse Perspectives (PEDP). Up to $15 million is available to support up to six awards, with each project eligible for a maximum budget of $2.5 million over a five-year period. Interested applicants should refer to the full announcement for guidelines and submit their proposals by October 18, 2024, while adhering to FAIR data principles for data sharing. For further inquiries, contact NIH Grants Information at grantsinfo@nih.gov.

    Point(s) of Contact
    grantsinfo@nih.gov
    Files
    Title
    Posted
    RFA-MH-25-195-Full-Announcement.html
    RFA-MH-25-195.html
    The Department of Health and Human Services, through the National Institutes of Health (NIH) and the National Institute of Mental Health (NIMH), has announced a funding opportunity titled "Individually Measured Phenotypes to Advance Computational Translation in Mental Health (IMPACT-MH)." This initiative aims to promote research that leverages behavioral assessments and computational methods to create individualized clinical signatures for predicting outcomes and guiding clinical decision-making in mental disorders. Applicants are encouraged to propose innovative behavioral tasks, utilize existing datasets, and derive new clinical signatures from integrated behavioral and clinical record data. The funding opportunity emphasizes the importance of diverse research teams and requires a Plan for Enhancing Diverse Perspectives (PEDP). Up to $15 million will be allocated, supporting up to six awards with a maximum budget of $2.5 million each for a project period of five years. The application process necessitates adherence to specific guidelines, including compliance with FAIR data principles for data sharing. Overall, this program seeks to foster individualized approaches in mental health research and clinical practice, moving beyond traditional diagnostic methods to enhance patient care.
    Similar Opportunities
    Utilizing Invasive Recording and Stimulating Opportunities in Humans to Advance Neural Circuitry Understanding of Mental Health Disorders (R21 Clinical Trial Optional)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a funding opportunity titled "Utilizing Invasive Recording and Stimulating Opportunities in Humans to Advance Neural Circuitry Understanding of Mental Health Disorders (R21 Clinical Trial Optional)." This grant aims to support innovative research utilizing invasive neural recording methods to explore the neural circuitry associated with mental health disorders, focusing on high-risk applications that address significant gaps in knowledge regarding complex moods and cognitive behaviors. The initiative seeks to bridge basic neuroscience with applied mental health interventions, encouraging diverse research teams to utilize advanced methodologies. The estimated funding amount is capped at $200,000, with applications due by January 7, 2028. For further inquiries, interested applicants can contact NIH Grants Information at grantsinfo@nih.gov or visit the additional information link at https://grants.nih.gov/grants/guide/pa-files/PAR-25-291.html.
    Utilizing Invasive Recording and Stimulating Opportunities in Humans to Advance Neural Circuitry Understanding of Mental Health Disorders (R01 Clinical Trial Optional)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a funding opportunity titled "Utilizing Invasive Recording and Stimulating Opportunities in Humans to Advance Neural Circuitry Understanding of Mental Health Disorders (R01 Clinical Trial Optional)." This initiative aims to support invasive neural recording studies that investigate the neural circuitry and dynamics associated with mental health disorders, encouraging researchers to address specific questions with high translational potential. The program emphasizes the importance of innovative collaborations in neuroscience and engineering to enhance understanding and therapeutic approaches for mental health challenges. Applications will open on January 5, 2025, with a project duration of up to five years and no budget limits. Interested applicants can reach out to NIH Grants Information at grantsinfo@nih.gov for further inquiries, and additional details can be found at the provided link: https://grants.nih.gov/grants/guide/pa-files/PAR-25-290.html.
    Genetic Architecture of Mental Disorders in Ancestrally Diverse Populations II (U01 Clinical Trial Not Allowed)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a funding opportunity titled "Genetic Architecture of Mental Disorders in Ancestrally Diverse Populations II (U01 Clinical Trial Not Allowed)" aimed at enhancing the understanding of psychiatric disorders in diverse populations, particularly those of African ancestry. This initiative seeks applications for cooperative agreements that will focus on accelerating gene discovery efforts and promoting global mental health equity, addressing the existing gap in genomic studies that predominantly center on European populations. The funding is intended to support innovative research approaches that incorporate community engagement and career development for underrepresented groups, with a project period of up to five years. Interested applicants can find more details and submit inquiries via the NIH Grants Information email at grantsinfo@nih.gov, with the application deadline set for February 13, 2026.
    Silvio O. Conte Centers for Basic Neuroscience or Translational Mental Health Research (P50 Clinical Trial Optional)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH), through the National Institute of Mental Health (NIMH), is offering a funding opportunity titled "Silvio O. Conte Centers for Basic Neuroscience or Translational Mental Health Research (P50 Clinical Trial Optional)." This initiative invites interdisciplinary teams to apply for grants aimed at advancing the understanding of mental disorders through innovative neuroscience research, focusing on the underlying mechanisms of mental illnesses, the integration of basic and clinical neuroscience, and the neurobehavioral development of psychopathology. The program is designed to support collaborative projects that address complex scientific questions that cannot be pursued through standard research mechanisms, with funding available for up to five years and direct costs capped at $2 million annually. Interested applicants can find more information and application guidelines at the provided link, and they must submit their proposals by June 9, 2025.
    Utilizing Invasive Recording and Stimulating Opportunities in Humans to Advance Neural Circuitry Understanding of Mental Health Disorders (R01 Clinical Trial Optional)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a funding opportunity titled "Utilizing Invasive Recording and Stimulating Opportunities in Humans to Advance Neural Circuitry Understanding of Mental Health Disorders" (FOA Number PAR-23-093). This grant aims to promote research focused on invasive neural recording studies that explore the neural circuitry underlying mental health disorders, with an emphasis on high translational potential in understanding moods, cognitive functions, and behaviors. The initiative encourages collaboration among diverse research teams in fields such as neurosurgery, electrophysiology, and psychology, while specifically excluding general neuroscience studies that do not focus on mental health or intervention development. Interested applicants can submit proposals until January 7, 2025, with no specific budget limits for projects that may extend up to five years; for further inquiries, contact NIH Grants Information at grantsinfo@nih.gov or visit the opportunity's webpage at https://grants.nih.gov/grants/guide/pa-files/PAR-23-093.html.
    Utilizing Invasive Recording and Stimulating Opportunities in Humans to Advance Neural Circuitry Understanding of Mental Health Disorders (R21 Clinical Trial Optional)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a grant opportunity titled "Utilizing Invasive Recording and Stimulating Opportunities in Humans to Advance Neural Circuitry Understanding of Mental Health Disorders (R21 Clinical Trial Optional)." This funding initiative aims to support invasive neural recording studies that address mental health-related questions, focusing on understanding the neural circuitry and dynamics underlying complex behaviors, emotions, and cognitive functions. The R21 grant mechanism encourages innovative, short-term research proposals with a budget of up to $275,000 over two years, while emphasizing the importance of diverse research teams from various clinical fields. Interested applicants should note that the application deadline is January 7, 2025, and can find further details and guidelines at the NIH grants website or by contacting NIH Grants Information at grantsinfo@nih.gov.
    Advanced Laboratories for Accelerating the Reach and Impact of Treatments for Youth and Adults with Mental Illness (ALACRITY) Research Centers (P50 Clinical Trial Optional)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a funding opportunity for the Advanced Laboratories for Accelerating the Reach and Impact of Treatments for Youth and Adults with Mental Illness (ALACRITY) Research Centers. This initiative aims to establish transdisciplinary research teams that will engage in high-impact studies to advance clinical practices and transform mental health care in the United States, focusing on the rapid development, testing, and refinement of innovative interventions and optimized service delivery for mental health disorders. The program emphasizes the integration of various fields to address significant mental health challenges, with funding available up to $1.5 million annually for a project period not exceeding five years. Interested applicants can find more information and apply by May 18, 2026, by contacting NIH Grants Information at grantsinfo@nih.gov or visiting the official announcement at https://grants.nih.gov/grants/guide/pa-files/PAR-24-210.html.
    Pilot Effectiveness Trials for Post-Acute Interventions and Services to Optimize Longer-term Outcomes (R01 Clinical Trial Required)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH), through the National Institute of Mental Health (NIMH), is inviting applications for the funding opportunity titled "Pilot Effectiveness Trials for Post-Acute Interventions and Services to Optimize Longer-term Outcomes" (PAR-25-206). This initiative aims to evaluate the preliminary effectiveness of therapeutic and service delivery interventions for the post-acute management of mental health conditions, focusing on aspects such as feasibility, tolerability, acceptability, safety, and potential effectiveness. The program is crucial for advancing mental health treatment and understanding, particularly for underserved populations, by gathering data that will inform larger-scale effectiveness trials. Interested applicants can apply for grants of up to $750,000 over a three-year period, with the submission window opening on January 5, 2025, and closing on January 7, 2028. For more information, applicants can contact NIH Grants Information at grantsinfo@nih.gov or visit the official announcement at https://grants.nih.gov/grants/guide/pa-files/PAR-25-206.html.
    NIMH Mentoring Networks for Mental Health Research Education (R25 Clinical Trial Not Allowed)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a grant opportunity titled "NIMH Mentoring Networks for Mental Health Research Education (R25 Clinical Trial Not Allowed)" aimed at enhancing the training of the psychological and behavioral research workforce in the U.S. This program supports innovative educational activities focused on developing mentoring networks for graduate and medical students, postdoctoral scholars, and early-career investigators, with an emphasis on fostering professional growth and facilitating independent research trajectories in mental health. The initiative is crucial for expanding and diversifying the mental health research workforce, requiring applicants to detail their mentoring network's goals, structure, and participant recruitment methods, particularly from underrepresented groups. The grant has an award ceiling of $200,000, with applications due by May 25, 2025. For further inquiries, interested parties can contact NIH Grants Information at grantsinfo@nih.gov or visit the additional information link at https://grants.nih.gov/grants/guide/pa-files/PAR-23-263.html.
    Bidirectional Influences Between Adolescent Social Media Use and Mental Health (R01 Clinical Trial Optional)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) has announced a funding opportunity titled "Bidirectional Influences Between Adolescent Social Media Use and Mental Health (R01 Clinical Trial Optional)" aimed at researching the complex interactions between social media usage and adolescent mental health. This initiative seeks to explore how social media impacts psychiatric symptoms and resilience against psychopathology, encouraging rigorous methodologies and the formation of youth advisory boards for inclusive research design. With a total funding of $5 million available for 5-6 awards over two years, eligible applicants include higher education institutions, nonprofits, and various governmental entities. The submission period opens on December 27, 2024, and interested parties can find more information and contact NIH Grants Information at grantsinfo@nih.gov or visit the opportunity's webpage at https://grants.nih.gov/grants/guide/rfa-files/RFA-MH-25-205.html.