The National Institutes of Health (NIH) is offering the Limited Competition: Basic Instrumentation Grant (BIG) Program to support eligible institutions in acquiring specialized scientific instruments crucial for advancing NIH-funded research. Institutions must demonstrate significant need from a group of Major Users, typically requiring at least three NIH-funded researchers, and must not have received S10 instrumentation funding exceeding $500,000 in the past three fiscal years. The program aims to enhance institutional research capabilities in the biomedical field by facilitating access to modern technologies, with grants ranging from a minimum of $25,000 to a maximum of $350,000. Applications are due by June 1 for the submission years 2025, 2026, and 2027, and interested parties can reach out to NIH Grants Information at grantsinfo@nih.gov for further inquiries.