The National Institutes of Health (NIH) is offering the Exploratory/Developmental Bioengineering Research Grants (EBRG) (R21 Clinical Trial Not Allowed) to support innovative research aimed at addressing significant biomedical challenges through bioengineering solutions. This funding opportunity encourages applications that explore novel scientific ideas or technologies, focusing on enhancing quality, efficacy, operability, and accessibility in basic, pre-clinical, and clinical research, without the need for extensive preliminary data. The grant provides a budget of up to $275,000 over a two-year period, with eligibility extending to a wide range of applicants, including higher education institutions, nonprofits, for-profits, and foreign entities. Interested applicants should adhere to NIH policies and guidelines, with a submission deadline of January 7, 2025. For further inquiries, contact the NIH OER Webmaster at OERWebmaster03@od.nih.gov, and additional details can be found at the provided link: http://grants.nih.gov/grants/guide/pa-files/PAR-22-090.html.