The National Institutes of Health (NIH) is offering Bioengineering Research Grants (BRG) (R01 Clinical Trial Optional) to foster interdisciplinary collaborations aimed at addressing critical biomedical challenges. This funding opportunity encourages the integration of life and physical sciences through multidisciplinary bioengineering approaches to develop innovative technologies and methods in biomedical research, including design-directed and hypothesis-driven studies. The initiative is significant for advancing bioengineering solutions in healthcare, ultimately enhancing patient outcomes through scientific collaboration. Interested applicants, including higher education institutions, nonprofits, and local governments, must submit their proposals by September 7, 2025, and can find more information at NIH Grants. For inquiries, contact NIH Grants Information at grantsinfo@nih.gov.