The Centers for Disease Control and Prevention (CDC) is offering a Notice of Funding Opportunity (NOFO) aimed at strengthening Botswana's national health data systems to enhance the government's response to HIV, tuberculosis (TB), and related public health threats under the PEPFAR initiative. The program seeks to provide tailored technical assistance to the Government of Botswana (GOB) by improving data governance, capacity building for data management, and enhancing system functionality and interoperability. This initiative is critical for establishing a sustainable, government-led response to ongoing health challenges through data-driven strategies and collaborations. Interested organizations can apply for a share of the anticipated $4,000,000 in funding for Year 1, with applications due by February 24, 2024, and expected awards starting on September 30, 2025. For further inquiries, applicants may contact Emily Dale at pepfarfoas@cdc.gov.