The Centers for Disease Control and Prevention (CDC) has announced a funding opportunity aimed at strengthening the organizational capacity of the Ministry of Health in the Kingdom of Eswatini to enhance its response to HIV, tuberculosis (TB), and related public health threats under the President’s Emergency Plan for AIDS Relief (PEPFAR). The initiative seeks to provide technical assistance in key areas such as leadership and governance, resource mobilization, and workforce planning, utilizing evidence-based approaches to improve the Ministry's operational effectiveness and adaptability to emerging health challenges. This cooperative agreement, with an anticipated total funding of $2 million for the first year, is open to a wide range of applicants, including local and international organizations, with a submission deadline of March 5, 2025. Interested parties can reach out to Emily Dale at pepfarfoas@cdc.gov for further information.