The Centers for Disease Control and Prevention (CDC) is offering a funding opportunity aimed at advancing sustainable digital health transformation across PEPFAR-supported countries, focusing on developing an informatics workforce to combat HIV/AIDS and tuberculosis by 2030. The initiative seeks to enhance health information systems (HIS) through capacity development, governance frameworks, and the integration of security standards, ensuring data-driven decision-making and resilience in health systems. This funding, with an anticipated total of $25 million for the first year and expected to result in 1-5 awards, is open to a wide range of eligible applicants, including state and local governments, educational institutions, and nonprofits, with applications due by February 21, 2025. For further inquiries, interested parties can contact Emily Dale at pepfarfoas@cdc.gov.