Combined Neuromodulation and Behavioral Treatment Algorithm Development for Stimulant Use Disorder (StUD) Enriched for Vulnerable Phenotype (U01 Clinical Trial Required)
ID: 355169Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Award Range

$0 - $500K

Eligible Applicants

Others

Funding Category

Health

Funding Instrument

Cooperative Agreement

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes

Original Source

https://grants.gov/search-results-detail/355169

Additional Information

http://grants.nih.gov/grants/guide/rfa-files/RFA-DA-25-057.html
Timeline
    Description

    The National Institutes of Health (NIH) is inviting proposals for a funding opportunity aimed at developing a combined neuromodulation and behavioral treatment algorithm for Stimulant Use Disorder (StUD), particularly focusing on vulnerable populations exhibiting high impulsivity and cognitive dysfunction. The initiative seeks to integrate non-invasive brain stimulation techniques, such as transcranial magnetic stimulation, with effective behavioral interventions like cognitive behavioral therapy, to create FDA-approved treatment solutions for StUD. Up to $2 million is available to fund three to five awards, with individual project budgets capped at $500,000 per year, and applications are due by November 28, 2024. For further inquiries, interested parties can contact NIH Grants Information at grantsinfo@nih.gov.

    Point(s) of Contact
    grantsinfo@nih.gov
    Files
    Title
    Posted
    RFA-DA-25-057-Full-Announcement.html
    RFA-DA-25-057.html
    The National Institutes of Health (NIH) is soliciting proposals for a new funding opportunity aimed at developing a combined neuromodulation and behavioral treatment algorithm for Stimulant Use Disorder (StUD), specifically targeting vulnerable phenotypes associated with high impulsivity and cognitive dysfunction. The initiative, under Funding Opportunity Number RFA-DA-25-057, encourages the pairing of non-invasive brain stimulation techniques (such as transcranial magnetic stimulation) with effective behavioral interventions (like cognitive behavioral therapy). The ultimate goal is to advance treatment strategies that can lead to FDA-approved device-based solutions for StUD. Applications must propose clinical trials that evaluate the efficacy of these combined treatments, focusing on critical factors such as treatment response, remission, and relapse prevention, particularly for patients deemed treatment-refractory. Up to $2 million will be available to fund three to five awards, with individual budgets capped at $500,000 per year. Project periods can extend up to five years, and all applications are due by November 28, 2024, with an earlier start date of November 27, 2024, for funded projects. The initiative underscores the urgency of improving treatment outcomes for individuals struggling with stimulant-related substance use disorders.
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