The National Institutes of Health (NIH) is inviting applications for a cooperative agreement to establish a Clinical Coordinating Center (CCC) as part of multi-site, investigator-initiated clinical trials focused on evaluating the efficacy of natural products, including botanicals and dietary supplements. Applicants are required to present comprehensive scientific and operational plans, demonstrating substantial preliminary data on the safety and bioavailability of the proposed natural products, and must also include a Plan for Enhancing Diverse Perspectives (PEDP) as part of their submission. This funding opportunity, designated as PAR-24-123, emphasizes the NIH's commitment to exploring complementary health strategies through rigorous scientific investigation, with applications due by July 15, 2026. For further inquiries, interested parties can contact NIH Grants Information at grantsinfo@nih.gov.