Clinical Coordinating Center for NCCIH Multi-Site Investigator-Initiated Clinical Trials of Natural Products (Collaborative UG3/UH3 Clinical Trial Required)
ID: 352183Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Eligible Applicants

Others

Funding Category

Health

Funding Instrument

Cooperative Agreement

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes

Original Source

https://grants.gov/search-results-detail/352183

Additional Information

http://grants.nih.gov/grants/guide/pa-files/PAR-24-123.html
Timeline
    Description

    The National Institutes of Health (NIH) is inviting applications for a cooperative agreement to establish a Clinical Coordinating Center (CCC) as part of multi-site, investigator-initiated clinical trials focused on evaluating the efficacy of natural products, including botanicals and dietary supplements. Applicants are required to present comprehensive scientific and operational plans, demonstrating substantial preliminary data on the safety and bioavailability of the proposed natural products, and must also include a Plan for Enhancing Diverse Perspectives (PEDP) as part of their submission. This funding opportunity, designated as PAR-24-123, emphasizes the NIH's commitment to exploring complementary health strategies through rigorous scientific investigation, with applications due by July 15, 2026. For further inquiries, interested parties can contact NIH Grants Information at grantsinfo@nih.gov.

    Point(s) of Contact
    grantsinfo@nih.gov
    Files
    Title
    Posted
    PAR-24-123-Full-Announcement.html
    PAR-24-123.html
    The National Institutes of Health (NIH) is inviting cooperative agreement applications for the establishment of a Clinical Coordinating Center (CCC) as part of multi-site, investigator-initiated clinical trials aimed at evaluating natural products, including botanicals and dietary supplements. This funding opportunity, designated as PAR-24-123, emphasizes rigorous investigation into the efficacy of natural products, requiring applicants to present comprehensive scientific and operational plans. A two-phase cooperative agreement funding mechanism, UG3/UH3, will be employed to facilitate trial setup and implementation. The CCC's responsibilities include managing project logistics, participant recruitment, and maintaining scientific integrity, while an accompanying Data Coordinating Center (DCC) is mandated to ensure independent data management and analysis. The NOFO emphasizes the necessity for a Plan for Enhancing Diverse Perspectives (PEDP), which will be a key component of the application evaluation. Additionally, applicants must demonstrate substantial preliminary data validating the proposed natural products, including evidence of safety and bioavailability. The NIH encourages early interaction with its scientific staff to refine proposals and align them with their strategic research priorities. This funding initiative highlights the NIH's dedication to exploring complementary health strategies through scientifically rigorous approaches.
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