NCCIH Natural Product Early Phase Clinical Trial Award (R33 Clinical Trial Required)
ID: 357492Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Award Range

$0 - $1M

Eligible Applicants

Others

Funding Category

Health

Funding Instrument

Grant

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes

Original Source

https://grants.gov/search-results-detail/357492

Additional Information

http://grants.nih.gov/grants/guide/pa-files/PAR-25-270.html
Timeline
    Description

    The National Institutes of Health (NIH) is offering the NCCIH Natural Product Early Phase Clinical Trial Award (R33), aimed at supporting investigator-initiated clinical trials of natural products such as botanicals and dietary supplements. This funding opportunity encourages applications for early phase trials that assess the impact of these products on specific biological targets and their potential clinical outcomes, with a focus on optimizing study designs and dosage. The initiative is crucial for advancing research in complementary and integrative health approaches, ensuring that projects adhere to rigorous scientific standards and include a Plan for Enhancing Diverse Perspectives (PEDP). The total estimated funding for this program is $1,050,000, with applications due by November 13, 2026. For further inquiries, interested applicants can contact NIH Grants Information at grantsinfo@nih.gov or visit the additional information page at https://grants.nih.gov/grants/guide/pa-files/PAR-25-270.html.

    Point(s) of Contact
    grantsinfo@nih.gov
    Files
    Title
    Posted
    PAR-25-270-Full-Announcement.html
    PAR-25-270.html
    The National Institutes of Health (NIH) is issuing a funding opportunity through the NCCIH Natural Product Early Phase Clinical Trial Award (R33) to support investigator-initiated trials of natural products like botanicals and dietary supplements with strong scientific foundations. The R33 mechanism is designed for early phase clinical trials, focusing on replicating the impact of these natural products on specific biological targets and their potential clinical effects over a maximum of three years. The funding aims to assess various study designs, dosage optimization, and the combination of these products with other therapies. Projects must comply with rigorous methodological standards and demonstrate a clear rationale through preliminary data. A key requirement is the inclusion of a Plan for Enhancing Diverse Perspectives (PEDP) to promote inclusivity and collaboration in research efforts. The document outlines specific details about eligibility, application processes, and review criteria, while emphasizing the importance of rigorous scientific inquiry in advancing complementary and integrative health approaches.
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