NCCIH Natural Product Mid Phase Clinical Trial (R01 Clinical Trial Required)
ID: 352162Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Award Range

$0 - $350K

Eligible Applicants

Others

Funding Category

Health

Funding Instrument

Grant

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes

Original Source

https://grants.gov/search-results-detail/352162

Additional Information

http://grants.nih.gov/grants/guide/pa-files/PAR-24-115.html
Timeline
    Description

    The National Institutes of Health (NIH) is inviting applications for the NCCIH Natural Product Mid Phase Clinical Trial (R01 Clinical Trial Required) grant, aimed at supporting mid-phase clinical trials of natural products such as botanicals and dietary supplements. The objective is to evaluate optimal doses, formulations, and patient responses, with a requirement for preliminary data demonstrating bioavailability and measurable target engagement. This funding opportunity is crucial for advancing research in natural products, particularly in areas like symptom management and minority health, while excluding trials focused on cancer treatment. Applicants can request up to $350,000 annually for a maximum project period of five years, with the submission deadline set for November 13, 2026. For further inquiries, interested parties can contact NIH Grants Information at grantsinfo@nih.gov or visit the additional information link at http://grants.nih.gov/grants/guide/pa-files/PAR-24-115.html.

    Point(s) of Contact
    grantsinfo@nih.gov
    Files
    Title
    Posted
    PAR-24-115-Full-Announcement.html
    PAR-24-115.html
    The National Institutes of Health's National Center for Complementary and Integrative Health (NCCIH) invites applications for mid-phase clinical trials focusing on natural products such as botanicals and dietary supplements through the NCCIH Natural Product Mid Phase Clinical Trial (R01 Clinical Trial Required) funding opportunity (PAR-24-115). This initiative seeks to support trials that evaluate optimal doses, formulations, and patient responses, backed by preliminary data demonstrating bioavailability and measurable target engagement. The proposal should exclude single-site efficacy trials and those aimed at cancer treatment. Key application components include a Plan for Enhancing Diverse Perspectives (PEDP), which must be included in submissions, and focus on priority areas such as symptom management and minority health. Funded projects can request budgets up to $350,000 annually, with a maximum project period of five years. The submission process emphasizes the importance of compliance with NIH registration and guidelines, and a well-defined timeline is essential for milestone completion. Applications will undergo a peer review process to assess significance, investigator qualifications, innovation, and the study's approach. The deadline for submission is set for March 2026, with a strong emphasis on ensuring diverse perspectives in research.
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