Integrated Functional Mapping and Molecular Profiling of Cell Ensembles Encoding the Effects of Addictive Substances in Rodents (R01 Clinical Trial Not Allowed)
ID: 351361Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Award Range

$0 - $700K

Eligible Applicants

Others

Funding Category

Health

Funding Instrument

Grant

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes

Original Source

https://grants.gov/search-results-detail/351361

Additional Information

http://grants.nih.gov/grants/guide/rfa-files/RFA-DA-25-023.html
Timeline
    Description

    The National Institutes of Health (NIH) is offering a funding opportunity titled "Integrated Functional Mapping and Molecular Profiling of Cell Ensembles Encoding the Effects of Addictive Substances in Rodents (R01 Clinical Trial Not Allowed)." This grant aims to support innovative research that utilizes scalable technologies to map and profile cell ensembles related to substance addiction across various exposure stages, including acute, chronic, withdrawal, abstinence, and relapse. The initiative seeks to fill critical gaps in understanding how neural ensembles are activated and how they influence addiction-related behaviors, ultimately contributing to the development of new interventions for substance use disorders. Interested applicants can apply for funding up to $700,000 per year, with a total funding pool of up to $2 million for 1-3 awards, and must submit their applications by February 24, 2026. For further inquiries, applicants can contact NIH Grants Information at grantsinfo@nih.gov or visit the opportunity's webpage at https://grants.nih.gov/grants/guide/rfa-files/RFA-DA-25-023.html.

    Point(s) of Contact
    grantsinfo@nih.gov
    Files
    Title
    Posted
    RFA-DA-25-023-Full-Announcement.html
    RFA-DA-25-023.html
    The Department of Health and Human Services, specifically the National Institute on Drug Abuse (NIDA), has announced a funding opportunity for research aimed at integrating functional mapping and molecular profiling of cell ensembles related to substance addiction in rodent models. This funding opportunity (RFA-DA-25-023) seeks to address gaps in understanding how neural ensembles are recruited and how they encode addiction-related behaviors. Researchers are encouraged to propose innovative technologies to collect multimodal data on cellular activity and molecular characteristics during various stages of substance exposure, including acute and chronic phases, craving, and relapse. Applications are due by February 24, 2026, with funding totaling up to $2 million for 1-3 awards, and budgets may not exceed $700,000 per year. All projects must avoid clinical trials and adhere to specified application guidelines. Eligible applicants range from higher education institutions to for-profit organizations and foreign entities. The document emphasizes the need for multidisciplinary teams and robust data-sharing plans, ensuring transparency and collaboration within the research community. The ultimate goal is to enhance the scientific understanding of the mechanisms underpinning substance use disorders to inform future interventions and treatments.
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