Development and Application of PET and SPECT Imaging Ligands as Biomarkers for Drug Discovery and for Pathophysiological Studies of CNS Disorders (R01 Clinical Trial Optional)
ID: 347402Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Eligible Applicants

Others

Funding Category

Health

Funding Instrument

Grant

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes

Original Source

https://grants.gov/search-results-detail/347402

Additional Information

http://grants.nih.gov/grants/guide/pa-files/PAR-23-164.html
Timeline
    Description

    The National Institutes of Health (NIH) has announced a funding opportunity for the development and application of positron emission tomography (PET) and single photon emission computed tomography (SPECT) imaging ligands as biomarkers for Central Nervous System (CNS) disorders. This initiative aims to enhance research on human brain disorders by inviting applications for research grants that propose the development and evaluation of novel radioligands, with a focus on facilitating drug discovery and understanding disease mechanisms. The program emphasizes collaboration among academia and the pharmaceutical industry to create functional imaging tools necessary for clinical trials and biomarker development. Interested applicants, including a diverse range of educational and research institutions, nonprofits, and for-profit organizations, must submit their proposals by May 7, 2026. For further inquiries, applicants can contact NIH Grants Information at grantsinfo@nih.gov or visit the additional information link at https://grants.nih.gov/grants/guide/pa-files/PAR-23-164.html.

    Point(s) of Contact
    grantsinfo@nih.gov
    Files
    Title
    Posted
    PAR-23-164-Full-Announcement.html
    PAR-23-164.html
    The Department of Health and Human Services, through its National Institutes of Health (NIH), has issued a funding opportunity (NOFO) for the development and application of PET and SPECT imaging ligands as biomarkers for Central Nervous System (CNS) disorders. The primary goal is to enhance research on human brain disorders by developing novel radioligands for PET and SPECT that can facilitate drug discovery and enhance understanding of disease mechanisms. This initiative emphasizes collaboration across academia and the pharmaceutical industry to produce functional imaging tools needed for clinical trials and biomarker development. The NOFO invites applications for research grants under the R01 Clinical Trial Optional activity code, with specific deadlines and guidelines for submission. Eligible applicants include a range of educational and research institutions, nonprofits, and for-profit organizations with an emphasis on diverse participation. Key evaluation criteria include the significance of the proposed research, the capability of investigators, innovative approaches, and the overall strategy for executing the project. Investors are encouraged to relate their applications closely to the needs outlined by the NIH, ensuring proposed studies are justified and relevant to current gaps in research. This initiative will greatly contribute to the advancement of imaging technologies for mental health research and treatment evaluation.
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