Development of Medications to Prevent and Treat Opioid and/or Stimulant Use Disorders and Overdose (UG3/UH3 - Clinical Trial Optional)
ID: 343322Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Award Range

$0 - $3M

Eligible Applicants

Others

Funding Category

Health

Funding Instrument

Cooperative Agreement

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes

Original Source

https://grants.gov/search-results-detail/343322

Additional Information

http://grants.nih.gov/grants/guide/pa-files/PAR-22-200.html
Timeline
    Description

    The National Institutes of Health (NIH), through the National Institute on Drug Abuse (NIDA), has announced a funding opportunity for the development of medications aimed at preventing and treating opioid and stimulant use disorders and overdose. This initiative, structured as a cooperative agreement (UG3/UH3), seeks innovative preclinical and clinical research proposals that address significant gaps in the treatment landscape, particularly for opioid use disorder (OUD) and psychostimulant use disorder (PsUD). The program is critical in responding to the ongoing overdose crisis and aims to facilitate the FDA's approval of novel pharmacotherapeutics, including new chemical entities and biologics, with a funding ceiling of $3 million per year over a maximum of five years. Interested applicants can find more information and guidelines at the NIH grants website and should direct inquiries to grantsinfo@nih.gov, with applications accepted until September 1, 2025.

    Point(s) of Contact
    grantsinfo@nih.gov
    Files
    Title
    Posted
    PAR-22-200-Full-Announcement.html
    PAR-22-200.html
    The Department of Health and Human Services, through the National Institutes of Health (NIH) and the National Institute on Drug Abuse (NIDA), has issued a funding opportunity aimed at the development of medications for preventing and treating opioid and stimulant use disorders and overdose. This cooperative agreement funding (UG3/UH3) encourages preclinical and clinical research that addresses crucial gaps in the treatment landscape, particularly with respect to opioid use disorder (OUD) and psychostimulant use disorder (PsUD). Key application dates include continuous submissions, scientific merit reviews occurring on specific dates, and a funding ceiling of $3 million yearly over a maximum of five years. The program seeks innovative research proposals targeting potential pharmacotherapeutics, including new chemical entities and biologics. Milestones will be essential for transitioning projects from the UG3 to the UH3 phase, as well as ensuring the effectiveness and safety of new medications. The overarching goal is to respond to the escalating overdose crisis and to facilitate the FDA's approval of novel treatments that would improve public health outcomes. Applications should adhere strictly to NIH guidelines and aim for a diverse pool of applicants to reflect varied perspectives in research.
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