Development of Medications to Prevent and Treat Opioid and/or Stimulant Use Disorders and Overdose (UG3/UH3 - Clinical Trial Optional)
ID: 343322Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Award Range

$0 - $3M

Eligible Applicants

Others

Funding Category

Health

Funding Instrument

Cooperative Agreement

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes

Original Source

https://grants.gov/search-results-detail/343322

Additional Information

http://grants.nih.gov/grants/guide/pa-files/PAR-22-200.html
Timeline
  1. 1
    Forecast Posted Not available
  2. 2
    Forecast Due Not available
  3. 3
    Posted Sep 1, 2022 12:00 AM
  4. 4
    Due Sep 1, 2025 12:00 AM
Description

The National Institutes of Health is offering a federal grant opportunity titled "Development of Medications to Prevent and Treat Opioid and/or Stimulant Use Disorders and Overdose (UG3/UH3 - Clinical Trial Optional)". This grant aims to support the discovery and development of medications to prevent and treat opioid and/or psychostimulant use disorders and overdose. The funding instrument type for this opportunity is a Cooperative Agreement. The grant falls under the category of funding activity related to health. The grant does not require cost sharing or matching. The eligible applicants for this grant include various institutions and organizations such as Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISISs), Eligible Agencies of the Federal Government, Faith-based or Community-based Organizations, Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Indian/Native American Tribal Governments (Other than Federally Recognized), Non-domestic (non-U.S.) Entities (Foreign Organizations), Regional Organizations, Tribally Controlled Colleges and Universities (TCCUs), and U.S. Territory or Possession.

The purpose of this grant is to support the discovery and development of medications that can prevent and treat opioid and/or psychostimulant use disorders and overdose. The grant involves two phases, UG3 and UH3. The UG3 phase provides support for a project with specific milestones to be accomplished within a 2-year period. The UH3 phase provides funding for 3 years to a project that successfully completes the milestones set in the UG3 phase. Projects that meet their milestones in the UG3 phase will be considered for transition to the UH3 phase. The grant encourages applications that include preclinical or clinical research studies with high impact and quick results to advance medications closer to FDA approval for the prevention and treatment of opioid use disorders and overdose. The compounds to be evaluated can be small molecules or biologics, and they can be tested in pre-clinical models or for the clinical manifestations of opioid use disorders such as withdrawal, craving, relapse, or overdose. The grant also supports the development of new chemical entities, new formulations of marketed medications available for other indications, or combinations of medications that hold promise for the treatment of opioid use disorders and overdose. The goal of this grant is to fast-track the discovery and development of medications to prevent and treat opioid use disorders or opioid overdose and advance them in the FDA's drug development approval pipeline.

For more information and to apply for this grant opportunity, please visit the following link: Development of Medications to Prevent and Treat Opioid and/or Stimulant Use Disorders and Overdose (UG3/UH3 - Clinical Trial Optional). If you have any inquiries, you can contact NIH Grants Information at grantsinfo@nih.gov.

Point(s) of Contact
grantsinfo@nih.gov
Files
Title
Posted
PAR-22-200-Full-Announcement.html
4/10/2024
Similar Opportunities
Developing Regulated Therapeutic and Diagnostic Solutions for Patients Affected by Opioid and/or Stimulants use Disorders (OUD/StUD) (R43/R44 - Clinical Trial Optional)
Active
National Institutes of Health
The National Institutes of Health (NIH) is offering a grant opportunity titled "Developing Regulated Therapeutic and Diagnostic Solutions for Patients Affected by Opioid and/or Stimulants use Disorders (OUD/StUD) (R43/R44 - Clinical Trial Optional)". This grant aims to support small businesses in developing novel, evidence-based, FDA-regulated medical products to address the needs of patients suffering from opioid use disorders (OUD) and stimulant use disorders (StUD). The grant encourages research projects focused on commercialization in two scientific areas: pharmacotherapeutics (small molecules and biologics) and medical therapeutic and diagnostic devices, including software as a medical device. The goal is to contribute to the national effort against the opioid and psychostimulant crisis by offering new medical products for individuals, families, and communities affected by these disorders. Small businesses are eligible to apply, and the grant does not require cost sharing or matching. The deadline for applications is February 14, 2025. For more information and to apply, visit the following link: [http://grants.nih.gov/grants/guide/rfa-files/RFA-DA-23-021.html](http://grants.nih.gov/grants/guide/rfa-files/RFA-DA-23-021.html). For any inquiries, contact the NIH OER Webmaster at OERWebmaster03@od.nih.gov.
Grand Opportunity in Medications Development for Substance-Use Disorders (U01 Clinical Trial Optional)
Active
National Institutes of Health
The National Institutes of Health (NIH) has posted a grant opportunity titled "Grand Opportunity in Medications Development for Substance-Use Disorders (U01 Clinical Trial Optional)". This funding opportunity aims to accelerate the development of medication for the treatment of Substance Use Disorders (SUDs) by supporting a diverse array of preclinical and/or clinical research projects. The goal is to fund medication studies that will have a high impact and quickly yield the necessary results to advance medications closer to FDA approval. The funding will be in the form of short-term (up to 3 years) and large (up to $5 million per year) cooperative agreements with close monitoring and significant scientific involvement of NIDA staff. This opportunity will enable critical medications development studies that would not be feasible using the traditional R01 activity code. Eligible applicants include Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISISs), Eligible Agencies of the Federal Government, Faith-based or Community-based Organizations, Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Indian/Native American Tribal Governments (Other than Federally Recognized), Non-domestic (non-U.S.) Entities (Foreign Organizations), Regional Organizations, Tribally Controlled Colleges and Universities (TCCUs), and U.S. Territory or Possession. The grant has a closing date of September 1, 2025, and an award ceiling of $5,000,000. For more information and to apply, visit the following link: [Grant Opportunity Details](https://grants.nih.gov/grants/guide/pa-files/PAR-22-202.html). For any inquiries, contact NIH Grants Information at grantsinfo@nih.gov.
Developing Regulated Therapeutic and Diagnostic Solutions for Patients Affected by Opioid and/or Stimulants use Disorders (OUD/StUD) (R41/R42 Clinical Trial Optional)
Active
National Institutes of Health
The National Institutes of Health (NIH) has posted a grant opportunity titled "Developing Regulated Therapeutic and Diagnostic Solutions for Patients Affected by Opioid and/or Stimulants use Disorders (OUD/StUD) (R41/R42 Clinical Trial Optional)". This grant aims to encourage Small Business Technology Transfer (STTR) grant applications from small business concerns (SBCs) to develop novel, evidence-based, FDA-regulated medical products for patients suffering from opioid use disorders (OUD) and/or stimulant use disorders (StUD). The grant focuses on two scientific areas: pharmacotherapeutics (small molecules and biologics) and medical therapeutic and diagnostic devices, including software as a medical device. The goal is to contribute to the effort against the national opioid and psychostimulant emergency and provide new medical products for individuals, families, and communities affected by this crisis. Small business companies that have developed or are developing FDA-regulated products for different indications and are interested in demonstrating their potential application in the OUD/StUD space are encouraged to apply. The grant does not require cost sharing or matching and is open to small businesses. Non-domestic entities and components are not eligible to apply. The closing date for applications is February 14, 2025. For more information and to apply, visit the [grant opportunity website](http://grants.nih.gov/grants/guide/rfa-files/RFA-DA-24-038.html). For inquiries, contact NIH Grants Information at grantsinfo@nih.gov.
HEAL Initiative: Translating Research to Practice to End the Overdose Crisis (R61/R33 Clinical Trial Optional)
Active
National Institutes of Health
The National Institutes of Health (NIH) is offering a grant opportunity titled "HEAL Initiative: Translating Research to Practice to End the Overdose Crisis (R61/R33 Clinical Trial Optional)". This grant falls under the category of Income Security and Social Services. The purpose of this grant is to support translational dissemination and implementation research focused on addressing overdose deaths and the intersection of pain and Opioid Use Disorder (OUD). The grant is expected to run for two years (FY23 and FY24) and has a maximum award ceiling of $750,000. Eligible applicants include various institutions and organizations, such as Alaska Native and Native Hawaiian Serving Institutions, Faith-based or Community-based Organizations, and Historically Black Colleges and Universities (HBCUs). Non-domestic (non-U.S.) entities and components are not eligible to apply. The deadline for applications is March 20, 2025. For more information and to apply, please visit the following link: [http://grants.nih.gov/grants/guide/rfa-files/RFA-DA-23-053.html](http://grants.nih.gov/grants/guide/rfa-files/RFA-DA-23-053.html).
Establishing a Center for the Advancement of Substance Use Disorder (SUD) Pharmacotherapeutics (U54 Clinical Trials Not Allowed)
Active
National Institutes of Health
The National Institutes of Health (NIH) has posted a grant opportunity titled "Establishing a Center for the Advancement of Substance Use Disorder (SUD) Pharmacotherapeutics (U54 Clinical Trials Not Allowed)". This grant aims to address the lack of early translational funding and technical support for new product developers in the field of substance use disorder (SUD) pharmacotherapeutics. The grant seeks to establish a technical development center (or centers) that will provide researchers with the necessary support to move their ideas beyond the conceptual stage and into product development. This support includes assistance in target product profile development, clinical need assessment, project plan development, prototype development, proof-of-concept study design, preliminary safety assessments, and guidance on current and future regulatory requirements. The funding instrument for this grant is a Cooperative Agreement, and there is no cost sharing or matching requirement. The grant falls under the category of Health and is open to various eligible applicants, including Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISISs), eligible agencies of the Federal Government, faith-based or community-based organizations, Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Indian/Native American Tribal Governments, non-domestic entities (foreign organizations), regional organizations, Tribally Controlled Colleges and Universities (TCCUs), and U.S. Territories or Possessions. The closing date for this grant opportunity is November 13, 2024. The maximum award ceiling is $1,900,000. For more information and to apply, interested parties can visit the following website: [http://grants.nih.gov/grants/guide/rfa-files/RFA-DA-25-056.html](http://grants.nih.gov/grants/guide/rfa-files/RFA-DA-25-056.html). For any inquiries, the contact email is grantsinfo@nih.gov.