The National Institutes of Health (NIH) has announced a funding opportunity titled "Research Opportunities in Established Cancer Epidemiology Cohort Studies (U01 Clinical Trial Not Allowed)" aimed at supporting cancer epidemiology research through established cohort studies that have met their initial recruitment goals. This initiative encourages hypothesis-driven research utilizing existing cohort data, with a focus on maintaining cohorts, continuing participant follow-up, and optimizing resource sharing across the cancer control continuum. Eligible applicants include a diverse range of institutions, such as higher education institutions, nonprofits, and foreign organizations, with projects expected to last up to five years and no specific budget limits, although costs must align with project needs. Interested parties should note that the application deadline is February 28, 2025, and can direct inquiries to the NIH OER Webmaster at OERWebmaster03@od.nih.gov. For further details, applicants can refer to the full announcement available at http://grants.nih.gov/grants/guide/pa-files/PAR-22-162.html.