The National Institutes of Health (NIH) is preparing to publish a Funding Opportunity Announcement (FOA) aimed at enhancing the uptake and use of the dapivirine vaginal ring for HIV prevention. This initiative seeks to advance research on understanding the multilevel facilitators and barriers to the use of the vaginal ring, develop interventions to support its uptake and persistent use, and test implementation strategies for optimal delivery. The FOA is significant as it addresses critical public health needs in HIV prevention, with an award ceiling of $450,000 and no cost-sharing or matching requirements. Interested applicants can reach out to Dr. Teri Senn at teri.senn@nih.gov or by phone at 301-761-7852 for further information, with the FOA expected to be published in Winter 2022 and applications due in Summer 2022.