The National Institutes of Health (NIH) is preparing to publish a Funding Opportunity Announcement (FOA) aimed at improving the uptake and use of the dapivirine vaginal ring for HIV prevention. This initiative seeks to advance research on the facilitators and barriers to the use of the vaginal ring, develop interventions to enhance its uptake and consistent use, and test implementation strategies for effective delivery. The funding opportunity is significant for public health, as it addresses critical aspects of HIV prevention through innovative research. Interested applicants can expect an award ceiling of $500,000, with the FOA anticipated to be published in Winter 2022 and applications due in Summer 2022. For further inquiries, potential applicants may contact Dr. Teri Senn at teri.senn@nih.gov or by phone at 301-761-7852.