The National Institutes of Health (NIH) is preparing to publish a Notice of Funding Opportunity (NOFO) for the NCI National Clinical Trials Network (NCTN) - Network Lead Academic Participating Sites, aimed at enhancing clinical trial capabilities in cancer research. This initiative seeks small businesses to provide scientific leadership and support in developing and conducting multi-center, late-phase clinical treatment trials, particularly focusing on diverse patient populations and various cancer modalities. The funding opportunity is critical for advancing the NCI's clinical research program, with an estimated total program funding of $35.1 million and an award ceiling of $1.7 million for approximately 35 expected awards. Interested applicants should prepare for the application process, as the NOFO is anticipated to be published in Fall 2024, with applications due in late February 2025.

The National Cancer Institute (NCI) intends to issue a UG1 NCI National Clinical Trials Network (NCTN) &#65533; Network Lead Academic Participating Sites notice of funding opportunity (NOFO). The NCTN Network Lead Academic Participating Sites will provide scientific leadership by helping to develop and conduct clinical trials in association with one or more adult Network Groups and will contribute substantial accrual to clinical trials conducted across the entire NCTN. The primary goal of the NCTN is the conduct of multi-center, late-phase, clinical treatment trials (i.e., randomized phase 2 and phase 3 trials) and advanced imaging trials across a broad range of cancers, modalities, and diverse patient populations as part of the NCI&apos;s overall clinical research program for adults, adolescents and young adults, and children with cancer. The NCTN also conducts, as necessary, preliminary studies needed for development of definitive trials, especially umbrella/basket trials and rare tumor trials, when an extensive, national patient catchment area is required. This Notice of Intent to Publish is being provided to allow sufficient time for applicants to develop strong applications. The NOFO is expected to be published in Fall 2024 with only one expected application due date in late February 2025. &#65533;

Notice of Intent to Publish a Funding Opportunity Announcement for NCI National Clinical Trials Network - Network Lead Academic Participating Sites (UG1 Clinical Trial Not Allowed)

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