The National Institutes of Health (NIH) plans to publish a funding opportunity announcement for a single-source grant aimed at establishing the NCI National Clinical Trials Network - Canadian Collaborating Clinical Trials Network. This initiative seeks to partner with private institutions of higher education to conduct large-scale, multi-site clinical trials, focusing on late-phase treatment trials and advanced imaging across various cancer types, while ensuring regulatory oversight in Canada. The funding, estimated at $3.8 million, is intended to support the NCTN's efforts to enhance clinical research for diverse patient populations, with the application due in late February 2025 and the award date anticipated for March 1, 2026. Interested applicants should prepare their proposals in advance of the expected announcement in Fall 2024.