The National Institutes of Health (NIH) is offering a funding opportunity titled "Strategies for Eliminating HIV Proteins (R01 Clinical Trial Not Allowed)" aimed at developing innovative therapeutic approaches to target HIV proteins and RNA for degradation. This initiative encourages applications that explore mechanisms such as RNA degradation or protein targeting, moving beyond traditional drug discovery methods. The NIH anticipates funding approximately $1.2 million for 1-2 awards in FY 2025, with a deadline for applications set for December 5, 2024, and an earliest project start date projected for July 2025. Interested applicants can find more information and contact NIH Grants Information at grantsinfo@nih.gov or visit the opportunity's webpage at https://grants.nih.gov/grants/guide/rfa-files/RFA-AI-24-057.html.