The National Institutes of Health (NIH) is preparing to publish a Notice of Funding Opportunity (NOFO) aimed at understanding the impact of social determinants of health (SDoH) on cancer disparities among people with HIV (PWH). This initiative seeks applications for research that explores health disparities throughout the cancer care continuum, including aspects such as screening, diagnosis, treatment, quality of life, and survivorship, with the goal of enhancing the NIH's research portfolio in this critical area. The funding opportunity, which will utilize the U01 cooperative agreement mechanism, anticipates awarding approximately four grants with a ceiling of $500,000 each, contributing to an estimated total program funding of $3 million. Interested applicants should prepare for the expected publication of the NOFO in fall 2024, with application deadlines projected for winter 2025, 2026, and 2027, and an anticipated award date of July 1, 2025.

The National Cancer Institute (NCI) intends to publish a new Notice of Funding Opportunity (NOFO) to solicit applications seeking to better understand the role of social determinants of health (SDoH) in contributing to or exacerbating cancer disparities and inequalities for people with HIV (PWH) across the cancer care continuum. The solicited applications may propose research investigating health disparities that span cancer control and health care delivery, spanning screening, diagnosis, treatment, quality of life, and survivorship. The primary objectives of this initiative will be to increase the NCI&#65533;s research portfolio investigating cancer disparities in PWH and to advance the understanding of the influence of SDoH, and how they may contribute to health disparities and inequities in PWH and cancer. For this NOFO, observational, interventional, and translational research studies are within scope. This Notice is being provided to allow potential applicants time to develop responsive projects and meaningful collaborations. The NOFO is expected to use the U01 mechanism with approximately three to four awards anticipated for each of three receipt dates. Clinical trials are optional. The NOFO is expected to be published in fall 2024 with expected application due dates in winter 2025, 2026, and 2027. This NOFO will utilize the U01 activity code. Details of the planned NOFO are provided below.

Notice of Intent to Publish a Notice of Funding Opportunity for Social Determinants of Health (SDoH) and Quality of Care Contributors to Cancer Disparities in People with HIV (U01; Clinical Trial Optional)

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