The National Institutes of Health (NIH) is preparing to publish a Notice of Funding Opportunity (NOFO) for the Environmental Health Disparities Centers (P50) program, aimed at addressing environmental health disparities and promoting environmental justice. This initiative will focus on research and capacity building to mitigate adverse environmental exposures affecting racial, ethnic, and socioeconomically disadvantaged populations, including those with disabilities and from rural areas. The program is significant for advancing health equity and addressing the needs of underserved communities, with the NOFO expected to be released in Summer 2024 and applications due in Fall 2024. Interested applicants, particularly private institutions of higher education, should prepare to submit proposals, as the estimated award date is set for July 1, 2025.