The Department of Health and Human Services, through the Agency for Healthcare Research and Quality (AHRQ), has issued a Notice of Funding Opportunity (NOFO) titled "Understanding and Improving Diagnostic Safety in Ambulatory Care: Incidence and Contributing Factors" (R01). The purpose is to invite research proposals that investigate the occurrence and contributing factors of diagnostic errors in ambulatory care, which impacts millions of patients annually, leading to significant health repercussions. This funding opportunity recognizes the growth of ambulatory services and the need to enhance diagnostic safety through a comprehensive understanding of practices across diverse healthcare environments. Applications are encouraged from researchers examining factors such as age, race, and social determinants affecting diagnostic accuracy. AHRQ aims to support innovative projects that improve training, leverage health information technologies, and implement work system enhancements to minimize diagnostic errors. The total funding limits are set at $500,000 per year, with a maximum of $2 million per project over four years. The application deadline is February 5, 2024, with the funding intended to advance health equity and improve healthcare quality and access across the U.S.