The National Institutes of Health (NIH) is preparing to publish a Notice of Funding Opportunity (NOFO) aimed at supporting the sustained development of informatics technologies for cancer research and management. This initiative seeks applications for the continued operation and enhancement of existing informatics resources that facilitate data acquisition, management, analysis, and dissemination across various aspects of cancer research, including biology, treatment, early detection, and health disparities. The emphasis is on maintaining resources that have demonstrated significant impact on cancer research, with a focus on user engagement and support. While applications are not currently being solicited, potential applicants are encouraged to prepare collaborative projects in anticipation of the NOFO, which is expected to be posted on August 29, 2025, with a closing date for submissions on November 21, 2025. For further inquiries, interested parties can contact Dr. Juli Klemm at juli.klemm@gmail.com or by phone at 202-853-7889.