Development of Psychosocial Therapeutic and Preventive Interventions for Mental Disorders (R61/R33 Clinical Trial Required)
ID: 331839Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Eligible Applicants

Others

Funding Category

Health

Funding Instrument

Grant

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes

Original Source

https://grants.gov/search-results-detail/331839

Additional Information

http://grants.nih.gov/grants/guide/pa-files/PAR-21-135.html
Timeline
    Description

    The National Institutes of Health (NIH) is offering a funding opportunity titled "Development of Psychosocial Therapeutic and Preventive Interventions for Mental Disorders (R61/R33 Clinical Trial Required)." This grant aims to support pilot research that develops and tests innovative psychosocial interventions targeting mental health issues, with a focus on translating emerging research into effective therapeutic strategies. The funding is structured in two phases: the R61 phase provides up to two years of support for preliminary testing, while the R33 phase offers up to three years for replication and clinical outcome assessment. A total of $27 million is available for this initiative, with applications due by October 15, 2024. For further inquiries, interested applicants can contact the NIH OER Webmaster at FBOWebmaster@OD.NIH.GOV.

    Point(s) of Contact
    FBOWebmaster@OD.NIH.GOV
    Files
    Title
    Posted
    PAR-21-135-Full-Announcement.html
    PAR-21-135.html
    The National Institute of Mental Health (NIMH) is encouraging applications for the R61/R33 funding opportunity focused on developing psychosocial therapeutic interventions for mental disorders. This grant aims to support pilot studies that explore innovative intervention strategies targeting novel mechanisms underlying mental health issues. The funding spans two phases: the R61 phase (up to 2 years) for preliminary testing and milestone-driven studies, and the R33 phase (up to 3 years) for replication and testing of the interventions' clinical benefits. Eligible applicants include a wide range of institutions and organizations, and clinical trials are required for all submissions. The total funding available is $27 million for FY 2021, reflecting NIMH's commitment to promoting innovative approaches within mental health research. Significant emphasis is placed on objectively measuring target engagement and clinical outcomes throughout the project duration. Effective utilization of this funding opportunity is expected to substantially advance the understanding and treatment of mental disorders by facilitating the translation of research into actionable interventions.
    Similar Opportunities
    Pilot Effectiveness Trials for Post-Acute Interventions and Services to Optimize Longer-term Outcomes (R34 Clinical Trial Required)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) is inviting applications for the "Pilot Effectiveness Trials for Post-Acute Interventions and Services to Optimize Longer-term Outcomes" grant, aimed at evaluating therapeutic and service delivery innovations for managing mental health conditions following acute treatment. Applicants are required to conduct pilot trials that assess the feasibility, acceptability, safety, and preliminary effectiveness of interventions designed to improve long-term mental health outcomes, particularly for underserved populations. This initiative underscores the importance of advancing mental health research and fostering effective care transitions beyond acute care settings. Eligible organizations can apply for funding of up to $450,000 over three years, with applications due by January 25, 2025. For further information, interested parties can contact the NIH OER Webmaster at FBOWebmaster@OD.NIH.GOV or visit the funding announcement at http://grants.nih.gov/grants/guide/pa-files/PAR-21-211.html.
    NIMH Exploratory/Developmental Research Grant (R21 Clinical Trial Not Allowed)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH), through the National Institute of Mental Health (NIMH), is offering the Exploratory/Developmental Research Grant (R21), which aims to support high-risk and innovative research projects that align with the mission of advancing mental health research. This grant is specifically designed for the early stages of research that may lead to significant breakthroughs in clinical and biomedical fields related to mental health, with a funding limit of $275,000 over a two-year period. Eligible applicants include a diverse range of organizations such as higher education institutions, non-profits, and tribal governments, emphasizing the importance of innovative approaches in addressing critical barriers in mental health research. Interested parties should note that applications are due by January 7, 2025, and must adhere to NIH guidelines, with further inquiries directed to grantsinfo@nih.gov.
    Effectiveness Trials for Post-Acute Interventions and Services to Optimize Longer-term Outcomes (R01 Clinical Trial Required)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH), through the National Institute of Mental Health (NIMH), is offering a funding opportunity for research projects aimed at evaluating the effectiveness of post-acute interventions and services for mental health conditions affecting youth, adults, and older adults. This initiative encourages clinical trials designed to assess therapeutic strategies that consolidate treatment gains, manage residual symptoms, prevent relapse, and enhance treatment adherence, with a focus on producing statistically powered studies that address chronic or relapsing mental health issues. The program emphasizes the importance of improving long-term mental health outcomes, particularly for underserved populations, and applications are open to a diverse range of eligible entities, including educational institutions and community organizations. Interested applicants should note that the deadline for submissions is January 25, 2025, and can find further details and guidelines at the provided NIH link or contact the NIH OER Webmaster at FBOWebmaster@OD.NIH.GOV for assistance.
    Clinical Studies of Mental Illness (Collaborative R01) (Clinical Trial Optional)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a funding opportunity titled "Clinical Studies of Mental Illness (Collaborative R01)" aimed at supporting multidisciplinary clinical studies focused on mental health, particularly in areas such as genetics, biomarkers, and various mental illnesses. This initiative encourages collaboration across multiple sites to enhance sample sizes and diversity in participant recruitment, specifically targeting health disparity populations. The program allows for a project period of up to five years with no explicit budget limits, although proposed budgets must be well justified. Interested applicants, including various educational and nonprofit institutions, should submit their applications by January 7, 2026, and can reach out to NIH Grants Information at grantsinfo@nih.gov for further inquiries. For more details, applicants can refer to the full announcement available at https://grants.nih.gov/grants/guide/pa-files/PAR-23-050.html.
    Pilot Research Opportunities in Crisis Response Services for Suicide Prevention (R34 Clinical Trial Optional)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a funding opportunity titled "Pilot Research Opportunities in Crisis Response Services for Suicide Prevention," aimed at supporting exploratory research into the effectiveness and implementation of crisis response services designed to prevent suicides. This initiative seeks to evaluate the impact of state and local policies on crisis service outcomes, focusing on real-world applications that consider various factors such as clinical presentations, geographic settings, cultural considerations, and health disparities. The total funding available is $2 million across fiscal years 2025-2026, with individual project budgets capped at $225,000 per year for a maximum of three years. Interested applicants can find more information and submission guidelines at the NIH grants website and should direct inquiries to grantsinfo@nih.gov. The application deadline is June 2, 2025.
    Advancing Learning Health Care Research in Outpatient Mental Health Treatment Settings (R34 Clinical Trial Optional)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) has announced a funding opportunity titled "Advancing Learning Health Care Research in Outpatient Mental Health Treatment Settings (R34 Clinical Trial Optional)," aimed at enhancing the implementation and sustainability of evidence-based practices in outpatient mental health and substance use treatment settings. This initiative encourages pilot studies that focus on data-driven learning health care, particularly in Certified Community Behavioral Health Clinics (CCBHCs), with objectives including addressing health disparities and improving crisis response services. Eligible applicants include a wide range of organizations, such as higher education institutions and community-based organizations, with funding available up to $450,000 over a three-year project period. The application submission period opens on May 16, 2024, and the final deadline for applications is January 8, 2026; for further inquiries, interested parties can contact NIH Grants Information at grantsinfo@nih.gov.
    Behavioral and Integrative Treatment Development Program (R34 Clinical Trial Optional)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) has announced the Behavioral and Integrative Treatment Development Program (R34 Clinical Trial Optional), a federal grant opportunity aimed at funding research for developing and testing behavioral treatments for substance use and dependence. This initiative seeks to encourage research that tests the efficacy of behavioral interventions, examines mechanisms of behavior change, and optimizes treatment approaches, particularly for individuals with comorbidities and those in drug abuse treatment. The program is crucial for advancing substance abuse treatment and addressing health disparities, with a maximum funding amount of $450,000 available over three years. Interested applicants, including various educational institutions and community organizations, must submit their proposals by March 21, 2025, and can find additional information at the provided NIH link or contact the NIH OER Webmaster at OERWebmaster03@od.nih.gov for inquiries.
    Innovative Mental Health Services Research Not Involving Clinical Trials (R01 Clinical Trials Not Allowed)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH), through the National Institute of Mental Health (NIMH), has announced a funding opportunity titled "Innovative Mental Health Services Research Not Involving Clinical Trials (R01 Clinical Trials Not Allowed)." This grant aims to support innovative research that enhances the delivery and quality of mental health services, particularly for underserved populations, by addressing issues such as access, usability, quality, and scalability of these services. Eligible applicants include a wide range of organizations, including educational institutions, non-profits, and governmental bodies, with a focus on projects that incorporate community input and comply with NIH guidelines. Interested parties should note that the application deadline is January 7, 2025, and further details can be found at the provided link: https://grants.nih.gov/grants/guide/pa-files/PAR-23-095.html. For inquiries, applicants can contact NIH Grants Information at grantsinfo@nih.gov.
    Phased Research to Support Substance Use Epidemiology, Prevention, and Services Studies (R61/R33 Clinical Trials Optional)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) has announced a funding opportunity titled "Phased Research to Support Substance Use Epidemiology, Prevention, and Services Studies (R61/R33 Clinical Trials Optional)," aimed at advancing translational research in the field of substance use. This initiative encourages researchers to engage in a two-phase research process, starting with an R61 planning phase lasting up to two years, followed by an R33 phase for larger studies that may extend up to four years, contingent upon meeting specific milestones. The program emphasizes the importance of community stakeholder engagement and mandates a Plan for Enhancing Diverse Perspectives (PEDP) in all proposals to ensure inclusivity in research development. Interested applicants can find more information and submit their proposals by December 14, 2026, and should direct inquiries to grantsinfo@nih.gov.
    Neuromodulation/Neurostimulation Device Development for Mental Health Applications (R21 Clinical Trial Not Allowed)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a funding opportunity titled "Neuromodulation/Neurostimulation Device Development for Mental Health Applications," aimed at advancing the development of innovative brain stimulation devices for mental health treatment. This grant supports projects that either create novel brain stimulation technologies or significantly enhance existing FDA-approved devices, focusing on improving spatial and temporal precision and enabling multi-focal approaches for effective treatment delivery. The initiative is crucial for addressing clinical limitations in mental health technologies and encourages collaboration among multidisciplinary teams with expertise in neuroscience, engineering, and regulatory affairs. Interested applicants can apply for up to $275,000 over a two-year project period, with applications due by January 7, 2025. For further inquiries, contact the NIH OER Webmaster at OERWebmaster03@od.nih.gov or visit the additional information link at http://grants.nih.gov/grants/guide/pa-files/PAR-22-038.html.