The National Institutes of Health (NIH), through the National Institute of Mental Health (NIMH), is offering a funding opportunity for pilot effectiveness trials aimed at evaluating post-acute interventions for mental health conditions. The primary objective is to assess the feasibility, safety, acceptability, and preliminary effectiveness of therapeutic and service delivery interventions designed to optimize long-term outcomes following acute treatment. This initiative is particularly significant as it seeks to address mental health disparities among underserved populations and aims to gather essential data for future large-scale effectiveness trials, with a total funding cap of $450,000 over a three-year period. Interested applicants must submit their proposals by January 25, 2025, and can reach out to the NIH OER Webmaster at FBOWebmaster@OD.NIH.GOV for any inquiries regarding the application process.