The National Institutes of Health (NIH) has announced a funding opportunity titled "Effectiveness Trials for Post-Acute Interventions and Services to Optimize Longer-term Outcomes," aimed at evaluating therapeutic and service delivery interventions for mental health conditions across various age groups. This initiative encourages clinical trials that assess the effectiveness of post-acute management strategies, particularly focusing on interventions that address chronicity in mental health disorders and promote better treatment adherence, especially among underserved populations. The funding opportunity is designed to support rigorous trials that can provide definitive evidence of intervention effectiveness, with applications due by January 25, 2025. For further details, applicants can contact the NIH OER Webmaster at FBOWebmaster@OD.NIH.GOV or visit the additional information link at http://grants.nih.gov/grants/guide/pa-files/PAR-21-210.html.