The National Institutes of Health (NIH) has announced a funding opportunity titled "Secondary Analysis of Existing Datasets in Heart, Lung, and Blood Diseases and Sleep Disorders (R21 Clinical Trial Not Allowed)." This grant aims to stimulate the use of existing human datasets for secondary analyses that explore innovative scientific ideas or new methodologies relevant to the NHLBI mission, specifically in the areas of heart, lung, and blood diseases, as well as sleep disorders. The initiative underscores the importance of leveraging existing data to enhance biomedical research efficiency, with a total funding availability of approximately $2,187,000 per year over three fiscal years, and individual project budgets capped at $75,000 in direct costs annually for a maximum duration of two years. Interested applicants, including a diverse range of institutions, must submit their applications by the deadlines of February 28, 2023, and October 28, 2023, and can reach out to NIH Grants Information at grantsinfo@nih.gov for further inquiries.