Effectiveness Trials for Post-Acute Interventions and Services to Optimize Longer-term Outcomes (R01 Clinical Trial Required)
ID: 356924Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Eligible Applicants

Others

Funding Category

Health

Funding Instrument

Grant

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes
Timeline
    Description

    The National Institutes of Health (NIH), through the National Institute of Mental Health (NIMH), has announced a funding opportunity titled "Effectiveness Trials for Post-Acute Interventions and Services to Optimize Longer-term Outcomes." This initiative aims to support research projects that evaluate the effectiveness of therapeutic and service delivery interventions for the post-acute management of mental health conditions affecting various age groups, with a focus on clinical trials that assess long-term recovery and treatment adherence. The funding opportunity is open to a diverse range of applicants, including higher education institutions and community-based organizations, with a maximum project period of five years. Interested parties should note that the application deadline is January 7, 2028, and can reach out to NIH Grants Information at grantsinfo@nih.gov for further inquiries. More details can be found at the provided link: https://grants.nih.gov/grants/guide/pa-files/PAR-25-207.html.

    Point(s) of Contact
    Files
    Title
    Posted
    The National Institutes of Health (NIH), through the National Institute of Mental Health (NIMH), has issued a funding opportunity titled "Effectiveness Trials for Post-Acute Interventions and Services to Optimize Longer-term Outcomes". This initiative aims to encourage research on therapeutic and service delivery interventions for post-acute management of mental health conditions affecting youth, adults, and older adults. The focus is on clinical trials that assess the effectiveness of these interventions, particularly those addressing long-term recovery and adherence to treatment plans. Key objectives include evaluating strategies that enhance treatment adherence, prevent relapse, and improve overall mental health outcomes using innovative approaches, such as technology-assisted monitoring. The funding opportunity is open to various organizations, including higher education institutions and nonprofits, with a maximum project period of five years. Applications are expected to follow strict guidelines regarding design and implementation, demonstrate feasibility, and consider disparities in mental health care access among underserved populations. Overall, the NIMH seeks to advance equity in mental health services through scientifically rigorous research that informs effective interventions aimed at improving long-term mental health outcomes. This funding opportunity represents a significant investment in addressing the chronic nature of many mental health conditions and enhancing recovery-oriented care.
    Similar Opportunities
    Pilot Effectiveness Trials for Post-Acute Interventions and Services to Optimize Longer-term Outcomes (R01 Clinical Trial Required)
    National Institutes of Health
    The National Institutes of Health (NIH), through the National Institute of Mental Health (NIMH), is inviting applications for the funding opportunity titled "Pilot Effectiveness Trials for Post-Acute Interventions and Services to Optimize Longer-term Outcomes" (PAR-25-206). This initiative aims to evaluate the preliminary effectiveness of therapeutic and service delivery interventions for the post-acute management of mental health conditions, focusing on aspects such as feasibility, tolerability, acceptability, safety, and potential effectiveness. The program is crucial for advancing mental health treatment and understanding, particularly for underserved populations, by gathering data that will inform larger-scale effectiveness trials. Interested applicants can apply for grants of up to $750,000 over a three-year period, with the submission window opening on January 5, 2025, and closing on January 7, 2028. For more information, applicants can contact NIH Grants Information at grantsinfo@nih.gov or visit the official announcement at https://grants.nih.gov/grants/guide/pa-files/PAR-25-206.html.
    Innovative Mental Health Services Research Not Involving Clinical Trials (R01 Clinical Trials Not Allowed)
    National Institutes of Health
    The National Institutes of Health (NIH) has announced a funding opportunity titled "Innovative Mental Health Services Research Not Involving Clinical Trials" (PAR-25-283), aimed at fostering innovative non-clinical trial research to enhance the delivery of mental health services. This initiative invites applications for R01-level projects that address critical areas for improving access, quality, and outcomes in mental health care, particularly focusing on disparities in service delivery. The funding is intended to support research that identifies factors influencing service access and quality, employing advanced methodologies and data analysis techniques to address pressing public health challenges. Interested applicants can request budgets reflecting actual project needs, with a maximum project period of five years, and should submit their applications by January 7, 2028. For further inquiries, applicants may contact NIH Grants Information at grantsinfo@nih.gov or visit the additional information link at https://grants.nih.gov/grants/guide/pa-files/PAR-25-283.html.
    Advanced Laboratories for Accelerating the Reach and Impact of Treatments for Youth and Adults with Mental Illness (ALACRITY) Research Centers (P50 Clinical Trial Optional)
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a funding opportunity for the Advanced Laboratories for Accelerating the Reach and Impact of Treatments for Youth and Adults with Mental Illness (ALACRITY) Research Centers. This initiative aims to establish transdisciplinary research teams that will engage in high-impact studies to advance clinical practices and transform mental health care in the United States, focusing on the rapid development, testing, and refinement of innovative interventions and optimized service delivery for mental health disorders. The program emphasizes the integration of various fields to address significant mental health challenges, with funding available up to $1.5 million annually for a project period not exceeding five years. Interested applicants can find more information and apply by May 18, 2026, by contacting NIH Grants Information at grantsinfo@nih.gov or visiting the official announcement at https://grants.nih.gov/grants/guide/pa-files/PAR-24-210.html.
    Clinical Studies of Mental Illness (Collaborative R01) (Clinical Trial Optional)
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a funding opportunity titled "Clinical Studies of Mental Illness (Collaborative R01)" aimed at supporting multidisciplinary clinical studies focused on mental health, particularly in areas such as genetics, biomarkers, and various mental illnesses. This initiative encourages collaboration across multiple sites to enhance sample sizes and diversity in participant recruitment, specifically targeting health disparity populations. The program allows for a project period of up to five years with no explicit budget limits, although proposed budgets must be well justified. Interested applicants, including various educational and nonprofit institutions, should submit their applications by January 7, 2026, and can reach out to NIH Grants Information at grantsinfo@nih.gov for further inquiries. For more details, applicants can refer to the full announcement available at https://grants.nih.gov/grants/guide/pa-files/PAR-23-050.html.
    Innovative Pilot Mental Health Services Research Not Involving Clinical Trials (R34 Clinical Trial Not Allowed)
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a funding opportunity titled "Innovative Pilot Mental Health Services Research Not Involving Clinical Trials" (R34 Clinical Trial Not Allowed) to support pilot research projects aimed at enhancing the accessibility, quality, and delivery of mental health services to diverse populations. This initiative encourages research that identifies factors affecting service utilization, develops new methodologies, and integrates large data sets, while explicitly prohibiting clinical trial proposals. With a total budget cap of $450,000 over three years, the program seeks to address health disparities and barriers within underserved groups, fostering partnerships with stakeholders to ensure practical application of findings. Interested applicants can find more information and submit inquiries via grantsinfo@nih.gov, with key deadlines starting in January 2025 and project expiration set for January 2028.
    National Cooperative Drug/Device Discovery/Development Groups (NCDDG) for the Treatment of Mental Disorders (U19 Clinical Trial Optional)
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a funding opportunity titled "National Cooperative Drug/Device Discovery/Development Groups (NCDDG) for the Treatment of Mental Disorders (U19 Clinical Trial Optional)," aimed at advancing the discovery and development of innovative treatments for mental disorders, including substance use disorders and alcohol use disorder. This initiative encourages collaborative efforts between academia and industry to support multidisciplinary research projects that focus on early-stage human studies and the development of novel therapeutic candidates and neuromodulation tools. The program is designed to complement private sector efforts and emphasizes the importance of data sharing and innovative approaches to mental health treatment challenges. Interested applicants must adhere to specific eligibility criteria and application instructions, with a submission opening date of January 25, 2025, and a total project period not exceeding five years. For further inquiries, applicants can contact NIH Grants Information at grantsinfo@nih.gov, and additional details can be found at the provided link: https://grants.nih.gov/grants/guide/pa-files/PAR-25-353.html.
    Advancing Learning Health Care Research in Outpatient Mental Health Treatment Settings (R34 Clinical Trial Optional)
    National Institutes of Health
    The National Institutes of Health (NIH) has announced a funding opportunity titled "Advancing Learning Health Care Research in Outpatient Mental Health Treatment Settings (R34 Clinical Trial Optional)," aimed at enhancing the implementation and sustainability of evidence-based practices in outpatient mental health and substance use treatment settings. This initiative encourages pilot studies that focus on data-driven learning health care, particularly in Certified Community Behavioral Health Clinics (CCBHCs), with objectives including addressing health disparities and improving crisis response services. Eligible applicants include a wide range of organizations, such as higher education institutions and community-based organizations, with funding available up to $450,000 over a three-year project period. The application submission period opens on May 16, 2024, and the final deadline for applications is January 8, 2026; for further inquiries, interested parties can contact NIH Grants Information at grantsinfo@nih.gov.
    Innovative Pilot Mental Health Services Research Not Involving Clinical Trials (R34 Clinical Trial Not Allowed)
    National Institutes of Health
    The National Institutes of Health (NIH) has announced a funding opportunity titled "Innovative Pilot Mental Health Services Research Not Involving Clinical Trials (R34 Clinical Trial Not Allowed)." This initiative aims to stimulate innovative pilot research that enhances the quality and accessibility of mental health services, particularly for underserved populations, by encouraging projects that identify factors affecting service delivery and assess new technologies without the need for clinical trials. The funding opportunity is open to a wide range of eligible applicants, including higher education institutions, nonprofits, and governmental entities, with a budget cap of $450,000 over a maximum project period of three years. Interested applicants should submit their proposals by May 7, 2025, and can find additional information and application guidelines at the NIH grants website or contact NIH Grants Information at grantsinfo@nih.gov for further inquiries.
    Neuromodulation/Neurostimulation Device Development for Mental Health Applications (R01 Clinical Trial Not Allowed)
    National Institutes of Health
    The National Institutes of Health (NIH) has announced a funding opportunity titled "Neuromodulation/Neurostimulation Device Development for Mental Health Applications (R01 Clinical Trial Not Allowed)" aimed at advancing the development of innovative brain stimulation devices for mental health treatment. This initiative seeks applications that either create novel devices or significantly enhance existing FDA-approved devices through hardware and software improvements, focusing on increased precision and effectiveness in treatment. The funding underscores the importance of multidisciplinary collaboration in neuroscience and engineering, with an emphasis on innovative approaches rather than incremental changes. Interested applicants can find more information and submit proposals by January 7, 2028, with no budget cap but a maximum project duration of five years. For inquiries, contact NIH Grants Information at grantsinfo@nih.gov or visit the opportunity's webpage at https://grants.nih.gov/grants/guide/pa-files/PAR-25-287.html.
    Utilizing Invasive Recording and Stimulating Opportunities in Humans to Advance Neural Circuitry Understanding of Mental Health Disorders (R01 Clinical Trial Optional)
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a funding opportunity titled "Utilizing Invasive Recording and Stimulating Opportunities in Humans to Advance Neural Circuitry Understanding of Mental Health Disorders (R01 Clinical Trial Optional)." This initiative aims to support invasive neural recording studies that investigate the neural circuitry and dynamics associated with mental health disorders, encouraging researchers to address specific questions with high translational potential. The program emphasizes the importance of innovative collaborations in neuroscience and engineering to enhance understanding and therapeutic approaches for mental health challenges. Applications will open on January 5, 2025, with a project duration of up to five years and no budget limits. Interested applicants can reach out to NIH Grants Information at grantsinfo@nih.gov for further inquiries, and additional details can be found at the provided link: https://grants.nih.gov/grants/guide/pa-files/PAR-25-290.html.