Modulating Human Microbiome Function to Enhance Immune Responses Against Cancer (R21 Clinical Trial Not Allowed)
ID: 336392Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Award Range

$0 - $275K

Eligible Applicants

Others

Funding Category

Health

Funding Instrument

Grant

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes

Original Source

https://grants.gov/search-results-detail/336392

Additional Information

http://grants.nih.gov/grants/guide/pa-files/PAR-22-062.html
Timeline
    Description

    The National Institutes of Health (NIH) has announced a funding opportunity titled "Modulating Human Microbiome Function to Enhance Immune Responses Against Cancer" (R21 Clinical Trial Not Allowed), aimed at supporting exploratory research on the human microbiome's role in anti-tumor immune responses. This initiative seeks to elucidate mechanisms by which specific microbes or their metabolites can influence tumor immunity, with a focus on identifying novel molecular targets for cancer prevention strategies. The research is particularly relevant for understanding the gut microbiome's impact on cancer development and immune responses, especially in individuals with altered gut microbiota. Eligible applicants include various educational institutions, nonprofits, and government entities, with a funding ceiling of $275,000 available over a two-year period. Applications must be submitted by January 7, 2025, and inquiries can be directed to the NIH OER Webmaster at OERWebmaster03@od.nih.gov.

    Point(s) of Contact
    OERWebmaster03@od.nih.gov
    Files
    Title
    Posted
    PAR-22-062-Full-Announcement.html
    PAR-22-062.html
    The Department of Health and Human Services, through the National Institutes of Health (NIH) and the National Cancer Institute (NCI), has issued a Funding Opportunity Announcement (FOA) for research on the role of the human microbiome in enhancing anti-tumor immune responses, titled "Modulating Human Microbiome Function to Enhance Immune Responses Against Cancer" (R21 Clinical Trial Not Allowed). This exploratory/developmental research aims to investigate mechanisms by which specific microbes or their metabolites can influence tumor immunity, ultimately identifying molecular targets for cancer prevention. Notable areas of interest include studying the gut microbiome's impact on cancer development and immune responses, particularly in patients with altered gut microbiota. The FOA invites applications focused on innovative research directions and requires rigorous assessment of how host-microbe interactions can be optimized for anti-tumor efficacy. Eligible organizations include educational institutions, nonprofits, and government entities, with a budget limit of $275,000 over two years. Applications must follow specific submission procedures via Grants.gov or NIH's ASSIST system, and peer-reviewed applications will be assessed based on their scientific merit, innovation, and relevance to public health goals. This opportunity emphasizes the critical intersection of microbiology and immunology in cancer research and prevention strategies.
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