The United States Agency for International Development (USAID) is issuing a Request for Information (RFI) to gather insights for potential HIV prevention initiatives targeting adolescent girls and young women (AGYW) aged 10-24, as well as other vulnerable youth populations in South Africa. The RFI aims to refine strategies and identify best practices for the DREAMS initiative, which seeks to significantly reduce new HIV infections through a comprehensive package of interventions that address biological, behavioral, and socio-economic factors. This initiative is crucial for enhancing community involvement, improving access to biomedical HIV prevention services, and integrating these efforts into government plans, ultimately fostering a supportive environment for AGYW to access essential health services. Interested parties can submit their responses by August 22, 2024, and should direct inquiries to pretoriaapplications@usaid.gov or call +27124522000 for further information.