The United States Agency for International Development (USAID) is seeking expert insights through a Request for Information (RFI) aimed at accelerating HIV vaccine research and development in low- and middle-income countries (LMIC). The RFI invites recommendations on five key areas: fostering a collaborative research environment in Africa, streamlining the manufacturing of HIV vaccine candidates, assessing the safety of an antibody cocktail for infants, innovating new protective methods, and enhancing community engagement in vaccine research. This initiative is crucial for addressing the ongoing challenges of HIV in LMICs and promoting local leadership and equitable partnerships in vaccine development. Interested parties must submit their responses electronically by May 24, 2024, to Simone Cho at scho@usaid.gov, adhering to the specified submission guidelines.