The U.S. Agency for International Development (USAID) issued a Request for Information (RFI) on January 31, 2022, regarding an initiative aimed at enhancing the health, socioeconomic, and educational outcomes of vulnerable children, adolescents, and families of Haitian descent in the Dominican Republic, particularly those affected by HIV. This five-year program intends to address and reduce barriers to HIV prevention and service delivery through comprehensive case management that focuses on child-centered, family-based services. The RFI invites organizations to respond by March 1, 2022, with specific feedback on the proposed activity, including key health interventions, challenges in service provision, innovative approaches, and strategies for sustainable solutions. Those interested are required to submit their responses electronically, adhering to a detailed format and structure outlined in the document. The initiative reflects USAID's commitment to epidemic control and improving health services for populations disproportionately affected by HIV, particularly among Haitian migrants and their descendants, addressing various sociocultural challenges, stigma, and access to care. As such, the program aligns with broader PEPFAR goals and U.S. government strategies to enhance health outcomes in relation to infectious diseases within marginalized communities.